Safety and Efficacy of the Superior Gluteal Artery Perforator (SGAP) Flap in Autologous Breast Reconstruction: Systematic Review and Meta-Analysis

SIMPLE SUMMARY: Breast reconstruction following mastectomy is associated with higher patient satisfaction and quality of life. Autologous breast reconstruction has become increasingly popular in recent decades and offers good long-term results. While the abdomen is typically chosen as the donor site for autologous breast reconstruction, it can be unsuitable for some patients. In this setting, different donor sites, such as the buttocks, can be used to reconstruct the breast. The superior gluteal artery perforator (SGAP) flap is a safe alternative to the deep inferior epigastric artery perforator (DIEP) flap and provides good esthetic results, making it a valuable option for breast cancer patients desiring a postmastectomy autologous breast reconstruction. ABSTRACT: (1) Background: The superior gluteal artery perforator (SGAP) flap is a prominent technique for autologous breast reconstruction. Unlike other commonly used techniques, current literature on the safety and efficacy of the SGAP flap is heterogenous and limited. The aim of this article was to perform a systematic literature review and meta-analysis of postoperative outcomes and complications associated with SGAP flap autologous breast reconstructions. (2) Methods: A systematic literature search of multiple databases was performed using the PRISMA guidelines. We included articles evaluating SGAP flaps in autologous breast reconstruction. Outcomes and complications were recorded and analyzed. Proportions and their 95% confidence intervals (CIs) were calculated in a random-effects meta-analysis. (3) Results: Fourteen studies meeting inclusion criteria, representing a total of 667 SGAP flaps, were included. The total flap loss rate was 1% (95% CI 0–3%), partial flap loss rate was 1% (95% CI 0–3%), hematoma rate was 3% (95% CI 1–6%), emergent surgical re-exploration rate was 5% (95% CI 2–9%), and overall donor-site complications were 12% (95% CI 4–23%). (4) Conclusions: This systematic review and meta-analysis provide comprehensive knowledge on the efficacy and safety of the SGAP flap in autologous breast reconstruction. It demonstrates its overall safety and low complication rate, validating its important role as an effective option in breast reconstruction.