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TRPM4 Participates in Irradiation-Induced Aortic Valve Remodeling in Mice

SIMPLE SUMMARY: Despite its benefit in cancer treatment, thoracic irradiation can induce aortic valve stenosis with fibrosis and calcification. The TRPM4 cation channel is known to participate in cellular remodeling including the transition of cardiac fibroblasts to myofibroblasts, similar to that o...

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Detalles Bibliográficos
Autores principales:	Mpweme Bangando, Harlyne, Simard, Christophe, Aize, Margaux, Lebrun, Alexandre, Manrique, Alain, Guinamard, Romain
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9497207/ https://www.ncbi.nlm.nih.gov/pubmed/36139640 http://dx.doi.org/10.3390/cancers14184477

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