Gene Profiling of a 3D Psoriatic Skin Model Enriched in T Cells: Downregulation of PTPRM Promotes Keratinocyte Proliferation through Excessive ERK1/2 Signaling

Psoriasis is a complex, immune-mediated skin disease involving a wide range of epithelial and immune cells. The underlying mechanisms that govern the epidermal defects and immunological dysfunction observed in this condition remain largely unknown. In recent years, the emergence of new, more sophist...

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Detalles Bibliográficos
Autores principales: Rioux, Geneviève, Turgeon, Florence, Le-Bel, Gaëtan, Grenier, Camille, Guérin, Sylvain L., Pouliot, Roxane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9497242/
https://www.ncbi.nlm.nih.gov/pubmed/36139479
http://dx.doi.org/10.3390/cells11182904

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9497242/
https://www.ncbi.nlm.nih.gov/pubmed/36139479
http://dx.doi.org/10.3390/cells11182904

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