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Cancer-Associated Fibroblasts: The Origin, Biological Characteristics and Role in Cancer—A Glance on Colorectal Cancer

SIMPLE SUMMARY: Tumor microenvironment is a major contributor to tumor growth, metastasis and resistance to therapy. It consists of many cancer-associated fibroblasts (CAFs), which derive from different types of cells. CAFs detected in different tumor types are linked to poor prognosis, as in the ca...

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Detalles Bibliográficos
Autores principales: Fotsitzoudis, Charalampos, Koulouridi, Asimina, Messaritakis, Ippokratis, Konstantinidis, Theocharis, Gouvas, Nikolaos, Tsiaoussis, John, Souglakos, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9497276/
https://www.ncbi.nlm.nih.gov/pubmed/36139552
http://dx.doi.org/10.3390/cancers14184394