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Targeting HSP90 as a Novel Therapy for Cancer: Mechanistic Insights and Translational Relevance

Heat shock protein (HSP90), a highly conserved molecular chaperon, is indispensable for the maturation of newly synthesized poly-peptides and provides a shelter for the turnover of misfolded or denatured proteins. In cancers, the client proteins of HSP90 extend to the entire process of oncogenesis t...

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Detalles Bibliográficos
Autores principales:	Zhang, Jian, Li, Houde, Liu, Yu, Zhao, Kejia, Wei, Shiyou, Sugarman, Eric T., Liu, Lunxu, Zhang, Gao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9497295/ https://www.ncbi.nlm.nih.gov/pubmed/36139353 http://dx.doi.org/10.3390/cells11182778

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