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The Relationship between Anemia and Helicobacter Pylori Infection in Children

(1) Background: Many studies suggest that Helicobacter pylori (H. pylori) infection is associated with a higher prevalence of anemia. The aim of this study is to explore this fact for a pediatric population from the northeast of Romania; (2) Methods: A correlational retrospective study between infec...

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Autores principales: Lupu, Ancuta, Miron, Ingrith Crenguta, Cianga, Anca Lavinia, Cernomaz, Andrei Tudor, Lupu, Vasile Valeriu, Munteanu, Dragos, Ghica, Dragos Catalin, Fotea, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9497312/
https://www.ncbi.nlm.nih.gov/pubmed/36138631
http://dx.doi.org/10.3390/children9091324
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author Lupu, Ancuta
Miron, Ingrith Crenguta
Cianga, Anca Lavinia
Cernomaz, Andrei Tudor
Lupu, Vasile Valeriu
Munteanu, Dragos
Ghica, Dragos Catalin
Fotea, Silvia
author_facet Lupu, Ancuta
Miron, Ingrith Crenguta
Cianga, Anca Lavinia
Cernomaz, Andrei Tudor
Lupu, Vasile Valeriu
Munteanu, Dragos
Ghica, Dragos Catalin
Fotea, Silvia
author_sort Lupu, Ancuta
collection PubMed
description (1) Background: Many studies suggest that Helicobacter pylori (H. pylori) infection is associated with a higher prevalence of anemia. The aim of this study is to explore this fact for a pediatric population from the northeast of Romania; (2) Methods: A correlational retrospective study between infection with H. pylori and anemia was performed on a group of 542 children in a pediatric gastroenterology regional center in Northeast Romania; (3) Results: Out of 542 children with confirmed H. pylori infection, microcytic hypochromic anemia was present in 48 children, of whom 7 (14.5%) also had iron deficiency.; (4) Conclusions: The study results demonstrate a significant association of H. pylori infection with iron-deficiency anemia and iron deficiency in children in accordance with the results established in the published literature. Although the direct relationship between them it is not clear yet, prevention represents one of the first clinical measures that need to be implemented when encountering a refractory moderate to severe iron-deficiency anemia and, especially, when associated with gastrointestinal tract symptoms.
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spelling pubmed-94973122022-09-23 The Relationship between Anemia and Helicobacter Pylori Infection in Children Lupu, Ancuta Miron, Ingrith Crenguta Cianga, Anca Lavinia Cernomaz, Andrei Tudor Lupu, Vasile Valeriu Munteanu, Dragos Ghica, Dragos Catalin Fotea, Silvia Children (Basel) Article (1) Background: Many studies suggest that Helicobacter pylori (H. pylori) infection is associated with a higher prevalence of anemia. The aim of this study is to explore this fact for a pediatric population from the northeast of Romania; (2) Methods: A correlational retrospective study between infection with H. pylori and anemia was performed on a group of 542 children in a pediatric gastroenterology regional center in Northeast Romania; (3) Results: Out of 542 children with confirmed H. pylori infection, microcytic hypochromic anemia was present in 48 children, of whom 7 (14.5%) also had iron deficiency.; (4) Conclusions: The study results demonstrate a significant association of H. pylori infection with iron-deficiency anemia and iron deficiency in children in accordance with the results established in the published literature. Although the direct relationship between them it is not clear yet, prevention represents one of the first clinical measures that need to be implemented when encountering a refractory moderate to severe iron-deficiency anemia and, especially, when associated with gastrointestinal tract symptoms. MDPI 2022-08-30 /pmc/articles/PMC9497312/ /pubmed/36138631 http://dx.doi.org/10.3390/children9091324 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Lupu, Ancuta
Miron, Ingrith Crenguta
Cianga, Anca Lavinia
Cernomaz, Andrei Tudor
Lupu, Vasile Valeriu
Munteanu, Dragos
Ghica, Dragos Catalin
Fotea, Silvia
The Relationship between Anemia and Helicobacter Pylori Infection in Children
title The Relationship between Anemia and Helicobacter Pylori Infection in Children
title_full The Relationship between Anemia and Helicobacter Pylori Infection in Children
title_fullStr The Relationship between Anemia and Helicobacter Pylori Infection in Children
title_full_unstemmed The Relationship between Anemia and Helicobacter Pylori Infection in Children
title_short The Relationship between Anemia and Helicobacter Pylori Infection in Children
title_sort relationship between anemia and helicobacter pylori infection in children
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9497312/
https://www.ncbi.nlm.nih.gov/pubmed/36138631
http://dx.doi.org/10.3390/children9091324
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