Establishment and Characterization of hTERT Immortalized Hutchinson–Gilford Progeria Fibroblast Cell Lines

Hutchinson–Gilford progeria syndrome (HGPS) is a rare premature aging syndrome caused by a dominant mutation in the LMNA gene. Previous research has shown that the ectopic expression of the catalytic subunit of telomerase (hTERT) can elongate the telomeres of the patients’ fibroblasts. Here, we esta...

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Detalles Bibliográficos
Autores principales: Lin, Haihuan, Mensch, Juliane, Haschke, Maria, Jäger, Kathrin, Köttgen, Brigitte, Dernedde, Jens, Orsó, Evelyn, Walter, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9497314/
https://www.ncbi.nlm.nih.gov/pubmed/36139359
http://dx.doi.org/10.3390/cells11182784

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