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Pediatric Sleep Questionnaire Predicts Moderate-to-Severe Obstructive Sleep Apnea in Children and Adolescents with Obesity

Pediatric obesity is associated with an increased risk of morbidity during childhood. Alongside the well-known metabolic syndrome, during the last decades scientific research has deeply investigated the risk of sleep breathing disorders. Among them, obstructive sleep apnea (OSA) commonly affects chi...

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Autores principales: Umano, Giuseppina Rosaria, Rondinelli, Giulia, Luciano, Margherita, Pennarella, Alessandro, Aiello, Francesca, Mangoni di Santo Stefano, Giuseppe Salvatore R. C., Di Sessa, Anna, Marzuillo, Pierluigi, Papparella, Alfonso, Miraglia del Giudice, Emanuele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9497855/
https://www.ncbi.nlm.nih.gov/pubmed/36138612
http://dx.doi.org/10.3390/children9091303
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author Umano, Giuseppina Rosaria
Rondinelli, Giulia
Luciano, Margherita
Pennarella, Alessandro
Aiello, Francesca
Mangoni di Santo Stefano, Giuseppe Salvatore R. C.
Di Sessa, Anna
Marzuillo, Pierluigi
Papparella, Alfonso
Miraglia del Giudice, Emanuele
author_facet Umano, Giuseppina Rosaria
Rondinelli, Giulia
Luciano, Margherita
Pennarella, Alessandro
Aiello, Francesca
Mangoni di Santo Stefano, Giuseppe Salvatore R. C.
Di Sessa, Anna
Marzuillo, Pierluigi
Papparella, Alfonso
Miraglia del Giudice, Emanuele
author_sort Umano, Giuseppina Rosaria
collection PubMed
description Pediatric obesity is associated with an increased risk of morbidity during childhood. Alongside the well-known metabolic syndrome, during the last decades scientific research has deeply investigated the risk of sleep breathing disorders. Among them, obstructive sleep apnea (OSA) commonly affects children with obesity. The presence of OSA heightens the risk of metabolic impairment and weight gain. Therefore, it deserves specific treatment. However, polysomnography (PSG) is not always available in clinical settings, and alternative diagnostic tools are needed. This study aimed to investigate the predictivity of the pediatric sleep questionnaire (PSQ) for moderate-to-severe OSA diagnosis. Children and adolescents with obesity and suspected OSA with available full-night cardiorespiratory PSG were retrospectively enrolled. Receiver operating curve analysis was performed to test the ability of PSQ in predicting moderate-to-severe OSA (AHI > 5 episode/h). The final sample included 60 children and adolescents. The PSQ showed a good area under the curve (AUC) of 0.88 (95% CI 0.78–0.98, p < 0.0001). Moreover, a value above or equal to 0.65 showed an 80% sensitivity and 100% specificity for moderate and severe OSA. These findings suggest that PSQ might be used in clinical settings with limited access to PSG for stratifying disease severity and for selecting children with urgent need of sleep study.
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spelling pubmed-94978552022-09-23 Pediatric Sleep Questionnaire Predicts Moderate-to-Severe Obstructive Sleep Apnea in Children and Adolescents with Obesity Umano, Giuseppina Rosaria Rondinelli, Giulia Luciano, Margherita Pennarella, Alessandro Aiello, Francesca Mangoni di Santo Stefano, Giuseppe Salvatore R. C. Di Sessa, Anna Marzuillo, Pierluigi Papparella, Alfonso Miraglia del Giudice, Emanuele Children (Basel) Article Pediatric obesity is associated with an increased risk of morbidity during childhood. Alongside the well-known metabolic syndrome, during the last decades scientific research has deeply investigated the risk of sleep breathing disorders. Among them, obstructive sleep apnea (OSA) commonly affects children with obesity. The presence of OSA heightens the risk of metabolic impairment and weight gain. Therefore, it deserves specific treatment. However, polysomnography (PSG) is not always available in clinical settings, and alternative diagnostic tools are needed. This study aimed to investigate the predictivity of the pediatric sleep questionnaire (PSQ) for moderate-to-severe OSA diagnosis. Children and adolescents with obesity and suspected OSA with available full-night cardiorespiratory PSG were retrospectively enrolled. Receiver operating curve analysis was performed to test the ability of PSQ in predicting moderate-to-severe OSA (AHI > 5 episode/h). The final sample included 60 children and adolescents. The PSQ showed a good area under the curve (AUC) of 0.88 (95% CI 0.78–0.98, p < 0.0001). Moreover, a value above or equal to 0.65 showed an 80% sensitivity and 100% specificity for moderate and severe OSA. These findings suggest that PSQ might be used in clinical settings with limited access to PSG for stratifying disease severity and for selecting children with urgent need of sleep study. MDPI 2022-08-27 /pmc/articles/PMC9497855/ /pubmed/36138612 http://dx.doi.org/10.3390/children9091303 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Umano, Giuseppina Rosaria
Rondinelli, Giulia
Luciano, Margherita
Pennarella, Alessandro
Aiello, Francesca
Mangoni di Santo Stefano, Giuseppe Salvatore R. C.
Di Sessa, Anna
Marzuillo, Pierluigi
Papparella, Alfonso
Miraglia del Giudice, Emanuele
Pediatric Sleep Questionnaire Predicts Moderate-to-Severe Obstructive Sleep Apnea in Children and Adolescents with Obesity
title Pediatric Sleep Questionnaire Predicts Moderate-to-Severe Obstructive Sleep Apnea in Children and Adolescents with Obesity
title_full Pediatric Sleep Questionnaire Predicts Moderate-to-Severe Obstructive Sleep Apnea in Children and Adolescents with Obesity
title_fullStr Pediatric Sleep Questionnaire Predicts Moderate-to-Severe Obstructive Sleep Apnea in Children and Adolescents with Obesity
title_full_unstemmed Pediatric Sleep Questionnaire Predicts Moderate-to-Severe Obstructive Sleep Apnea in Children and Adolescents with Obesity
title_short Pediatric Sleep Questionnaire Predicts Moderate-to-Severe Obstructive Sleep Apnea in Children and Adolescents with Obesity
title_sort pediatric sleep questionnaire predicts moderate-to-severe obstructive sleep apnea in children and adolescents with obesity
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9497855/
https://www.ncbi.nlm.nih.gov/pubmed/36138612
http://dx.doi.org/10.3390/children9091303
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