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Pediatric Sleep Questionnaire Predicts Moderate-to-Severe Obstructive Sleep Apnea in Children and Adolescents with Obesity
Pediatric obesity is associated with an increased risk of morbidity during childhood. Alongside the well-known metabolic syndrome, during the last decades scientific research has deeply investigated the risk of sleep breathing disorders. Among them, obstructive sleep apnea (OSA) commonly affects chi...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9497855/ https://www.ncbi.nlm.nih.gov/pubmed/36138612 http://dx.doi.org/10.3390/children9091303 |
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author | Umano, Giuseppina Rosaria Rondinelli, Giulia Luciano, Margherita Pennarella, Alessandro Aiello, Francesca Mangoni di Santo Stefano, Giuseppe Salvatore R. C. Di Sessa, Anna Marzuillo, Pierluigi Papparella, Alfonso Miraglia del Giudice, Emanuele |
author_facet | Umano, Giuseppina Rosaria Rondinelli, Giulia Luciano, Margherita Pennarella, Alessandro Aiello, Francesca Mangoni di Santo Stefano, Giuseppe Salvatore R. C. Di Sessa, Anna Marzuillo, Pierluigi Papparella, Alfonso Miraglia del Giudice, Emanuele |
author_sort | Umano, Giuseppina Rosaria |
collection | PubMed |
description | Pediatric obesity is associated with an increased risk of morbidity during childhood. Alongside the well-known metabolic syndrome, during the last decades scientific research has deeply investigated the risk of sleep breathing disorders. Among them, obstructive sleep apnea (OSA) commonly affects children with obesity. The presence of OSA heightens the risk of metabolic impairment and weight gain. Therefore, it deserves specific treatment. However, polysomnography (PSG) is not always available in clinical settings, and alternative diagnostic tools are needed. This study aimed to investigate the predictivity of the pediatric sleep questionnaire (PSQ) for moderate-to-severe OSA diagnosis. Children and adolescents with obesity and suspected OSA with available full-night cardiorespiratory PSG were retrospectively enrolled. Receiver operating curve analysis was performed to test the ability of PSQ in predicting moderate-to-severe OSA (AHI > 5 episode/h). The final sample included 60 children and adolescents. The PSQ showed a good area under the curve (AUC) of 0.88 (95% CI 0.78–0.98, p < 0.0001). Moreover, a value above or equal to 0.65 showed an 80% sensitivity and 100% specificity for moderate and severe OSA. These findings suggest that PSQ might be used in clinical settings with limited access to PSG for stratifying disease severity and for selecting children with urgent need of sleep study. |
format | Online Article Text |
id | pubmed-9497855 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-94978552022-09-23 Pediatric Sleep Questionnaire Predicts Moderate-to-Severe Obstructive Sleep Apnea in Children and Adolescents with Obesity Umano, Giuseppina Rosaria Rondinelli, Giulia Luciano, Margherita Pennarella, Alessandro Aiello, Francesca Mangoni di Santo Stefano, Giuseppe Salvatore R. C. Di Sessa, Anna Marzuillo, Pierluigi Papparella, Alfonso Miraglia del Giudice, Emanuele Children (Basel) Article Pediatric obesity is associated with an increased risk of morbidity during childhood. Alongside the well-known metabolic syndrome, during the last decades scientific research has deeply investigated the risk of sleep breathing disorders. Among them, obstructive sleep apnea (OSA) commonly affects children with obesity. The presence of OSA heightens the risk of metabolic impairment and weight gain. Therefore, it deserves specific treatment. However, polysomnography (PSG) is not always available in clinical settings, and alternative diagnostic tools are needed. This study aimed to investigate the predictivity of the pediatric sleep questionnaire (PSQ) for moderate-to-severe OSA diagnosis. Children and adolescents with obesity and suspected OSA with available full-night cardiorespiratory PSG were retrospectively enrolled. Receiver operating curve analysis was performed to test the ability of PSQ in predicting moderate-to-severe OSA (AHI > 5 episode/h). The final sample included 60 children and adolescents. The PSQ showed a good area under the curve (AUC) of 0.88 (95% CI 0.78–0.98, p < 0.0001). Moreover, a value above or equal to 0.65 showed an 80% sensitivity and 100% specificity for moderate and severe OSA. These findings suggest that PSQ might be used in clinical settings with limited access to PSG for stratifying disease severity and for selecting children with urgent need of sleep study. MDPI 2022-08-27 /pmc/articles/PMC9497855/ /pubmed/36138612 http://dx.doi.org/10.3390/children9091303 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Umano, Giuseppina Rosaria Rondinelli, Giulia Luciano, Margherita Pennarella, Alessandro Aiello, Francesca Mangoni di Santo Stefano, Giuseppe Salvatore R. C. Di Sessa, Anna Marzuillo, Pierluigi Papparella, Alfonso Miraglia del Giudice, Emanuele Pediatric Sleep Questionnaire Predicts Moderate-to-Severe Obstructive Sleep Apnea in Children and Adolescents with Obesity |
title | Pediatric Sleep Questionnaire Predicts Moderate-to-Severe Obstructive Sleep Apnea in Children and Adolescents with Obesity |
title_full | Pediatric Sleep Questionnaire Predicts Moderate-to-Severe Obstructive Sleep Apnea in Children and Adolescents with Obesity |
title_fullStr | Pediatric Sleep Questionnaire Predicts Moderate-to-Severe Obstructive Sleep Apnea in Children and Adolescents with Obesity |
title_full_unstemmed | Pediatric Sleep Questionnaire Predicts Moderate-to-Severe Obstructive Sleep Apnea in Children and Adolescents with Obesity |
title_short | Pediatric Sleep Questionnaire Predicts Moderate-to-Severe Obstructive Sleep Apnea in Children and Adolescents with Obesity |
title_sort | pediatric sleep questionnaire predicts moderate-to-severe obstructive sleep apnea in children and adolescents with obesity |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9497855/ https://www.ncbi.nlm.nih.gov/pubmed/36138612 http://dx.doi.org/10.3390/children9091303 |
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