Cargando…

(–)-Xanthatin as a Killer of Human Breast Cancer MCF-7 Mammosphere Cells: A Comparative Study with Salinomycin

Experimental evidence accumulated by our research group and others strongly suggests that (–)-xanthatin, a xanthanolide sesquiterpene lactone, exhibits anti-proliferative effects on human breast cancer cells (in vitro) as well as anti-tumor effects in experimental animals (in vivo). In cancer biolog...

Descripción completa

Detalles Bibliográficos
Autores principales:	Takeda, Shuso, Hirao-Suzuki, Masayo, Shindo, Mitsuru, Aramaki, Hironori
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9497939/ https://www.ncbi.nlm.nih.gov/pubmed/36135176 http://dx.doi.org/10.3390/cimb44090264

Ejemplares similares

2-Methoxyestradiol as an Antiproliferative Agent for Long-Term Estrogen-Deprived Breast Cancer Cells
por: Hirao-Suzuki, Masayo, et al.
Publicado: (2023)

miR-126 Decreases Proliferation and Mammosphere Formation of MCF-7 and Predicts Prognosis of ER+ Breast Cancer
por: Msheik, Zahraa S., et al.
Publicado: (2022)

Divergence of Intracellular Trafficking of Sphingosine Kinase 1 and Sphingosine-1-Phosphate Receptor 3 in MCF-7 Breast Cancer Cells and MCF-7-Derived Stem Cell-Enriched Mammospheres
por: Sukocheva, Olga A., et al.
Publicado: (2021)

5-Azacytidine Induces Anoikis, Inhibits Mammosphere Formation and Reduces Metalloproteinase 9 Activity in MCF-7 Human Breast Cancer Cells
por: Chang, Hsueh-Wei, et al.
Publicado: (2014)

Salinomycin enhances doxorubicin-induced cytotoxicity in multidrug resistant MCF-7/MDR human breast cancer cells via decreased efflux of doxorubicin
por: KIM, KWANG-YOUN, et al.
Publicado: (2015)

Xanthatin Induces Leishmanicidal Activity by Affecting Carbon Metabolism in Amastigotes
por: Akbari, Ziba, et al.
Publicado: (2021)

A Novel Nanoparticle Preparation to Enhance the Gastric Adhesion and Bioavailability of Xanthatin
por: Zhou, Yaqian, et al.
Publicado: (2020)

Xanthatin Selectively Targets Retinoblastoma by Inhibiting the PLK1-Mediated Cell Cycle
por: Yang, Jie, et al.
Publicado: (2021)

Mammosphere culture of metastatic breast cancer cells enriches for tumorigenic breast cancer cells
por: Grimshaw, Matthew J, et al.
Publicado: (2008)

Breast cancer mammospheres secrete Adrenomedullin to induce lipolysis and browning of adjacent adipocytes
por: Paré, Martin, et al.
Publicado: (2020)

Mammosphere Formation in Breast Carcinoma Cell Lines Depends upon Expression of E-cadherin
por: Manuel Iglesias, Juan, et al.
Publicado: (2013)

Mesenchymal traits are selected along with stem features in breast cancer cells grown as mammospheres
por: Borgna, Silvia, et al.
Publicado: (2012)

Lipid tethering of breast tumor cells reduces cell aggregation during mammosphere formation
por: Bhandary, Lekhana, et al.
Publicado: (2021)

Xanthatin Alleviates LPS-Induced Inflammatory Response in RAW264.7 Macrophages by Inhibiting NF-κB, MAPK and STATs Activation
por: Liu, Yuanqi, et al.
Publicado: (2022)

Determining Mammosphere-Forming Potential: Application of the Limiting Dilution Analysis
por: Rota, Lauren M., et al.
Publicado: (2012)

Mesenchymal traits and cancer stem cells in mammospheres: Chicken or egg?
por: Kohandel, Mohammad
Publicado: (2012)

Human Mammospheres Secrete Hormone-Regulated Active Extracellular Vesicles
por: Gonzalez, Esperanza, et al.
Publicado: (2014)

The human DEK oncogene stimulates beta catenin signaling, invasion and mammosphere formation in breast cancer
por: Privette Vinnedge, Lisa M., et al.
Publicado: (2011)

A Breast Cancer Stem Cell-Selective, Mammospheres-Potent Osmium(VI) Nitrido Complex
por: Suntharalingam, Kogularamanan, et al.
Publicado: (2014)

Variable Intrinsic Expression of Immunoregulatory Biomarkers in Breast Cancer Cell Lines, Mammospheres, and Co-Cultures
por: Montoyo-Pujol, Yoel Genaro, et al.
Publicado: (2023)

Xanthatin inhibits STAT3 and NF‐κB signalling by covalently binding to JAK and IKK kinases
por: Liu, Man, et al.
Publicado: (2019)

Optimization of xanthatin extraction from Xanthium spinosum L. and its cytotoxic, anti-angiogenesis and antiviral properties
por: Romero, M., et al.
Publicado: (2015)

Anticancer Mechanisms of Salinomycin in Breast Cancer and Its Clinical Applications
por: Wang, Hui, et al.
Publicado: (2021)

Patient-derived Mammosphere and Xenograft Tumour Initiation Correlates with Progression to Metastasis
por: Eyre, Rachel, et al.
Publicado: (2016)

Mesenchymal Stem Cells Promote Mammosphere Formation and Decrease E-Cadherin in Normal and Malignant Breast Cells
por: Klopp, Ann H., et al.
Publicado: (2010)

Structural centrosome aberrations favor proliferation by abrogating microtubule-dependent tissue integrity of breast epithelial mammospheres
por: Schnerch, D, et al.
Publicado: (2016)

Cytotoxic and chemomodulatory effects of Phyllanthus niruri in MCF-7 and MCF-7(ADR) breast cancer cells
por: Abdel-Sattar, Ola E., et al.
Publicado: (2023)

Salinomycin induces autophagic cell death in salinomycin-sensitive melanoma cells through inhibition of autophagic flux
por: Liu, Yajing, et al.
Publicado: (2020)

Propofol Reduced Mammosphere Formation of Breast Cancer Stem Cells via PD-L1/Nanog In Vitro
por: Zhang, Xiaobei, et al.
Publicado: (2019)

A Triphenylphosphonium-Functionalized Delivery System for an ATM Kinase Inhibitor That Ameliorates Doxorubicin Resistance in Breast Carcinoma Mammospheres
por: Stagni, Venturina, et al.
Publicado: (2023)

Salinomycin-loaded Nanofibers for Glioblastoma Therapy
por: Norouzi, Mohammad, et al.
Publicado: (2018)

In Vitro Analysis of Breast Cancer Cell Line Tumourspheres and Primary Human Breast Epithelia Mammospheres Demonstrates Inter- and Intrasphere Heterogeneity
por: Smart, Chanel E., et al.
Publicado: (2013)

Transcriptomics indicate nuclear division and cell adhesion not recapitulated in MCF7 and MCF10A compared to luminal A breast tumours
por: Goh, Jeremy Joon Ho, et al.
Publicado: (2022)

Comparative studies of salinomycin-loaded nanoparticles prepared by nanoprecipitation and single emulsion method
por: Wang, Qin, et al.
Publicado: (2014)

Down-Regulation of Vitamin D Receptor in Mammospheres: Implications for Vitamin D Resistance in Breast Cancer and Potential for Combination Therapy
por: Pervin, Shehla, et al.
Publicado: (2013)

Ex vivo Optimization of Glucose-Regulated Protein 94/Glycoprotein 96 Expressions in Mammospheres; Implication for Breast Cancer Immunotherapy
por: Izadpanah, Amirhossein, et al.
Publicado: (2022)

Orai1α and Orai1β support calcium entry and mammosphere formation in breast cancer stem cells
por: Jardin, Isaac, et al.
Publicado: (2023)

Correction: In Vitro Analysis of Breast Cancer Cell Line Tumourspheres and Primary Human Breast Epithelia Mammospheres Demonstrates Inter- and Intrasphere Heterogeneity
por: Smart, Chanel E., et al.
Publicado: (2013)

Breast cancer stem cell selectivity of synthetic nanomolar-active salinomycin analogs
por: Huang, Xiaoli, et al.
Publicado: (2016)

SUN-010 BRCA1 Mutation Influences Progesterone Response in Human Benign Mammospheres
por: Davaadelger, Batzaya, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_bt06q8cua0mi8nrsa5vatpknfs