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From the Difficult Airway Management to Diagnosis of Retropharyngeal Synovial Cell Carcinoma

Respiratory complications are among the most common problems addressed in neonatology in the first hours after birth, whereas the risk of any cancer in the neonatal period is 28 per million. Sarcomas, malignant mesenchymal neoplasms, account for about 8% of all neoplasms in the neonatal period. We r...

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Autores principales: Jassem-Bobowicz, Joanna Maria, Sokołowska, Ewa Magdalena, Hinca, Katarzyna Monika, Drążkowska, Izabela, Stefańska, Katarzyna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9498277/
https://www.ncbi.nlm.nih.gov/pubmed/36138670
http://dx.doi.org/10.3390/children9091361
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author Jassem-Bobowicz, Joanna Maria
Sokołowska, Ewa Magdalena
Hinca, Katarzyna Monika
Drążkowska, Izabela
Stefańska, Katarzyna
author_facet Jassem-Bobowicz, Joanna Maria
Sokołowska, Ewa Magdalena
Hinca, Katarzyna Monika
Drążkowska, Izabela
Stefańska, Katarzyna
author_sort Jassem-Bobowicz, Joanna Maria
collection PubMed
description Respiratory complications are among the most common problems addressed in neonatology in the first hours after birth, whereas the risk of any cancer in the neonatal period is 28 per million. Sarcomas, malignant mesenchymal neoplasms, account for about 8% of all neoplasms in the neonatal period. We report on a male neonate born at 36 + 4/7 weeks of gestation, diagnosed with retropharyngeal synovial carcinoma. Ineffective respiratory movements and generalized cyanosis were the first symptoms to be noted. On the ultrasound examination of the neck, a tumor of the retropharyngeal space was exposed, then visualized by an MRI of the head and neck. The biopsy analysis revealed the diagnosis of an extremely rare tumor in a neonate. The location of its growth was atypical, contributing to a diagnostic challenge. The neoplasm was treated solely with chemotherapy concordantly with the CWS protocol, individually customized for our patient. Preterm birth, as in our case, 36 + 4/7 weeks of gestation, may imply a possible need for resuscitation or support in the transition period. Aggressive high-grade tumors of the head and neck region are locally invasive and prone to metastasize. However, prognosis in infants is hard to estimate, therefore both individualized treatment and multidisciplinary care should be tailored to the needs of the patient.
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spelling pubmed-94982772022-09-23 From the Difficult Airway Management to Diagnosis of Retropharyngeal Synovial Cell Carcinoma Jassem-Bobowicz, Joanna Maria Sokołowska, Ewa Magdalena Hinca, Katarzyna Monika Drążkowska, Izabela Stefańska, Katarzyna Children (Basel) Case Report Respiratory complications are among the most common problems addressed in neonatology in the first hours after birth, whereas the risk of any cancer in the neonatal period is 28 per million. Sarcomas, malignant mesenchymal neoplasms, account for about 8% of all neoplasms in the neonatal period. We report on a male neonate born at 36 + 4/7 weeks of gestation, diagnosed with retropharyngeal synovial carcinoma. Ineffective respiratory movements and generalized cyanosis were the first symptoms to be noted. On the ultrasound examination of the neck, a tumor of the retropharyngeal space was exposed, then visualized by an MRI of the head and neck. The biopsy analysis revealed the diagnosis of an extremely rare tumor in a neonate. The location of its growth was atypical, contributing to a diagnostic challenge. The neoplasm was treated solely with chemotherapy concordantly with the CWS protocol, individually customized for our patient. Preterm birth, as in our case, 36 + 4/7 weeks of gestation, may imply a possible need for resuscitation or support in the transition period. Aggressive high-grade tumors of the head and neck region are locally invasive and prone to metastasize. However, prognosis in infants is hard to estimate, therefore both individualized treatment and multidisciplinary care should be tailored to the needs of the patient. MDPI 2022-09-07 /pmc/articles/PMC9498277/ /pubmed/36138670 http://dx.doi.org/10.3390/children9091361 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Jassem-Bobowicz, Joanna Maria
Sokołowska, Ewa Magdalena
Hinca, Katarzyna Monika
Drążkowska, Izabela
Stefańska, Katarzyna
From the Difficult Airway Management to Diagnosis of Retropharyngeal Synovial Cell Carcinoma
title From the Difficult Airway Management to Diagnosis of Retropharyngeal Synovial Cell Carcinoma
title_full From the Difficult Airway Management to Diagnosis of Retropharyngeal Synovial Cell Carcinoma
title_fullStr From the Difficult Airway Management to Diagnosis of Retropharyngeal Synovial Cell Carcinoma
title_full_unstemmed From the Difficult Airway Management to Diagnosis of Retropharyngeal Synovial Cell Carcinoma
title_short From the Difficult Airway Management to Diagnosis of Retropharyngeal Synovial Cell Carcinoma
title_sort from the difficult airway management to diagnosis of retropharyngeal synovial cell carcinoma
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9498277/
https://www.ncbi.nlm.nih.gov/pubmed/36138670
http://dx.doi.org/10.3390/children9091361
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