Cargando…

R-Loop Formation in Meiosis: Roles in Meiotic Transcription-Associated DNA Damage

Meiosis is specialized cell division during gametogenesis that produces genetically unique gametes via homologous recombination. Meiotic homologous recombination entails repairing programmed 200–300 DNA double-strand breaks generated during the early prophase. To avoid interference between meiotic g...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fujiwara, Yasuhiro, Handel, Mary Ann, Okada, Yuki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9498298/ https://www.ncbi.nlm.nih.gov/pubmed/36135313 http://dx.doi.org/10.3390/epigenomes6030026

Ejemplares similares

Dual roles of R-loops in the formation and processing of programmed DNA double-strand breaks during meiosis
por: Liu, Chao, et al.
Publicado: (2023)

Uncoupling of transcriptomic and cytological differentiation in mouse spermatocytes with impaired meiosis
por: Fine, Alexander D., et al.
Publicado: (2019)

Exposure to podophyllotoxin inhibits oocyte meiosis by disturbing meiotic spindle formation
por: Hu, Lin-Lin, et al.
Publicado: (2018)

Meiotic cohesins mediate initial loading of HORMAD1 to the chromosomes and coordinate SC formation during meiotic prophase
por: Fujiwara, Yasuhiro, et al.
Publicado: (2020)

Transition from a meiotic to a somatic-like DNA damage response during the pachytene stage in mouse meiosis
por: Enguita-Marruedo, Andrea, et al.
Publicado: (2019)

The fission yeast MTREC and EJC orthologs ensure the maturation of meiotic transcripts during meiosis
por: Marayati, Bahjat Fadi, et al.
Publicado: (2016)

Novel Meiotic miRNAs and Indications for a Role of PhasiRNAs in Meiosis
por: Dukowic-Schulze, Stefanie, et al.
Publicado: (2016)

Regulatory complexity revealed by integrated cytological and RNA-seq analyses of meiotic substages in mouse spermatocytes
por: Ball, Robyn L., et al.
Publicado: (2016)

Tet1 controls meiosis by regulating meiotic gene expression
por: Yamaguchi, Shinpei, et al.
Publicado: (2012)

Corrigendum: Novel Meiotic miRNAs and Indications for a Role of PhasiRNAs in Meiosis
por: Dukowic-Schulze, Stefanie, et al.
Publicado: (2020)

RPA complexes in Caenorhabditis elegans meiosis; unique roles in replication, meiotic recombination and apoptosis
por: Hefel, Adam, et al.
Publicado: (2021)

Implementation of meiosis prophase I programme requires a conserved retinoid-independent stabilizer of meiotic transcripts
por: Abby, Emilie, et al.
Publicado: (2016)

Co-transcriptional R-loops are the main cause of estrogen-induced DNA damage
por: Stork, Caroline Townsend, et al.
Publicado: (2016)

Correction to ‘RPA complexes in Caenorhabditis elegans meiosis; unique roles in replication, meiotic recombination and apoptosis’
por: Hefel, Adam, et al.
Publicado: (2021)

Bdf1 Bromodomains Are Essential for Meiosis and the Expression of Meiotic-Specific Genes
por: García-Oliver, Encar, et al.
Publicado: (2017)

Asynapsis and meiotic restitution in tomato male meiosis induced by heat stress
por: Schindfessel, Cédric, et al.
Publicado: (2023)

Analysis of Meiosis in SUN1 Deficient Mice Reveals a Distinct Role of SUN2 in Mammalian Meiotic LINC Complex Formation and Function
por: Link, Jana, et al.
Publicado: (2014)

Genome-wide map of R-loops reveals its interplay with transcription and genome integrity during germ cell meiosis
por: Jiang, Yu, et al.
Publicado: (2022)

Reductional Meiosis I Chromosome Segregation Is Established by Coordination of Key Meiotic Kinases
por: Galander, Stefan, et al.
Publicado: (2019)

Mouse Y-Linked Zfy1 and Zfy2 Are Expressed during the Male-Specific Interphase between Meiosis I and Meiosis II and Promote the 2(nd) Meiotic Division
por: Vernet, Nadège, et al.
Publicado: (2014)

Structure of an Intranucleosomal DNA Loop That Senses DNA Damage during Transcription
por: Gerasimova, Nadezhda S., et al.
Publicado: (2022)

A Mutation in Mtap2 Is Associated with Arrest of Mammalian Spermatocytes before the First Meiotic Division
por: Sun, Fengyun, et al.
Publicado: (2011)

Meiotic Telomere Protein Ndj1p Is Required for Meiosis-Specific Telomere Distribution, Bouquet Formation and Efficient Homologue Pairing
por: Trelles-Sticken, Edgar, et al.
Publicado: (2000)

Budding Yeast SLX4 Contributes to the Appropriate Distribution of Crossovers and Meiotic Double-Strand Break Formation on Bivalents During Meiosis
por: Higashide, Mika, et al.
Publicado: (2016)

MEIOB exhibits single-stranded DNA-binding and exonuclease activities and is essential for meiotic recombination
por: Luo, Mengcheng, et al.
Publicado: (2013)

The formation and repair of DNA double-strand breaks in mammalian meiosis
por: Qu, Wei, et al.
Publicado: (2021)

Meiosis in Sciara coprophila: structure of the spindle and chromosome behavior during the first meiotic division
Publicado: (1982)

Meiotic recombination modulates the structure and dynamics of the synaptonemal complex during C. elegans meiosis
por: Pattabiraman, Divya, et al.
Publicado: (2017)

Atypical meiosis can be adaptive in outcrossed Schizosaccharomyces pombe due to wtf meiotic drivers
por: Bravo Núñez, María Angélica, et al.
Publicado: (2020)

R-loop induced G-quadruplex in non-template promotes transcription by successive R-loop formation
por: Lee, Chun-Ying, et al.
Publicado: (2020)

DNA-DEPENDENT FORMATION OF THE SYNAPTINEMAL COMPLEX AT MEIOTIC PROPHASE
por: Roth, Thomas F., et al.
Publicado: (1967)

BRCA1 Recruitment to Transcriptional Pause Sites Is Required for R-Loop-Driven DNA Damage Repair
por: Hatchi, Elodie, et al.
Publicado: (2015)

Loop extrusion as a mechanism for DNA damage repair foci formation
por: Arnould, Coline, et al.
Publicado: (2021)

Regulation of the DNA damage response on male meiotic sex chromosomes
por: Lu, Lin-Yu, et al.
Publicado: (2013)

Positive regulation of meiotic DNA double-strand break formation by activation of the DNA damage checkpoint kinase Mec1(ATR)
por: Gray, Stephen, et al.
Publicado: (2013)

The oxidative damage initiation hypothesis for meiosis
por: Hörandl, Elvira, et al.
Publicado: (2013)

Novel mechanistic insights into the role of Mer2 as the keystone of meiotic DNA break formation
por: Rousová, Dorota, et al.
Publicado: (2021)

Identification of transcripts involved in meiosis and follicle formation during ovine ovary development
por: Baillet, Adrienne, et al.
Publicado: (2008)

BRD4 prevents the accumulation of R-loops and protects against transcription–replication collision events and DNA damage
por: Lam, Fred C., et al.
Publicado: (2020)

Senataxin Plays an Essential Role with DNA Damage Response Proteins in Meiotic Recombination and Gene Silencing
por: Becherel, Olivier J., et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_9omuskv6bb08iv70lunmns7rue