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Coexistent Detrusor Overactivity-Underactivity in Patients with Pelvic Floor Disorders
Introduction and Hypothesis: Pelvic floor disorders represent a series of conditions that share, in part, the same etiological mechanisms, so they tend to be concomitant. Recently, awareness of a new lower urinary tract clinical syndrome has risen, namely the coexisting overactive–underactive bladde...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9498318/ https://www.ncbi.nlm.nih.gov/pubmed/36141332 http://dx.doi.org/10.3390/healthcare10091720 |
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author | Frigerio, Matteo Barba, Marta Marino, Giuseppe Volontè, Silvia Melocchi, Tomaso De Vicari, Desirèe Torella, Marco Salvatore, Stefano Braga, Andrea Serati, Maurizio Manodoro, Stefano Cola, Alice |
author_facet | Frigerio, Matteo Barba, Marta Marino, Giuseppe Volontè, Silvia Melocchi, Tomaso De Vicari, Desirèe Torella, Marco Salvatore, Stefano Braga, Andrea Serati, Maurizio Manodoro, Stefano Cola, Alice |
author_sort | Frigerio, Matteo |
collection | PubMed |
description | Introduction and Hypothesis: Pelvic floor disorders represent a series of conditions that share, in part, the same etiological mechanisms, so they tend to be concomitant. Recently, awareness of a new lower urinary tract clinical syndrome has risen, namely the coexisting overactive–underactive bladder (COUB). The etiopathogenetic process, prevalence, and related instrumental findings of COUB are not well-established. We aimed to evaluate the prevalence, clinical features, and urodynamic findings of patients with COUB in a large cohort of patients with pelvic floor disorders. Methods: A cohort of 2092 women was retrospectively analyzed. A clinical interview, urogenital examination, and urodynamic assessment were performed by a trained urogynecologist. Based on baseline symptoms, patients were divided into COUB and non-COUB groups, and the degree of concordance between COUB and urodynamic findings, and other parameters related to the clinical aspects of these patients were measured and analyzed. Results: 18.8% of patients were classified as COUB. The association between COUB and patients with coexisting detrusor overactivity–underactivity (DOU) was statistically significant and there were substantial similarities in terms of population characteristics, symptoms, and urodynamic findings. Conclusions: Our study showed a high prevalence of COUB, and a link between this clinical syndrome and DOU was demonstrated. They showed substantial similarities in terms of clinical and urodynamics correlates. Based on these findings, we do think that urodynamic tests can be useful to improve knowledge on COUB and may be of help in the management of this condition. |
format | Online Article Text |
id | pubmed-9498318 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-94983182022-09-23 Coexistent Detrusor Overactivity-Underactivity in Patients with Pelvic Floor Disorders Frigerio, Matteo Barba, Marta Marino, Giuseppe Volontè, Silvia Melocchi, Tomaso De Vicari, Desirèe Torella, Marco Salvatore, Stefano Braga, Andrea Serati, Maurizio Manodoro, Stefano Cola, Alice Healthcare (Basel) Article Introduction and Hypothesis: Pelvic floor disorders represent a series of conditions that share, in part, the same etiological mechanisms, so they tend to be concomitant. Recently, awareness of a new lower urinary tract clinical syndrome has risen, namely the coexisting overactive–underactive bladder (COUB). The etiopathogenetic process, prevalence, and related instrumental findings of COUB are not well-established. We aimed to evaluate the prevalence, clinical features, and urodynamic findings of patients with COUB in a large cohort of patients with pelvic floor disorders. Methods: A cohort of 2092 women was retrospectively analyzed. A clinical interview, urogenital examination, and urodynamic assessment were performed by a trained urogynecologist. Based on baseline symptoms, patients were divided into COUB and non-COUB groups, and the degree of concordance between COUB and urodynamic findings, and other parameters related to the clinical aspects of these patients were measured and analyzed. Results: 18.8% of patients were classified as COUB. The association between COUB and patients with coexisting detrusor overactivity–underactivity (DOU) was statistically significant and there were substantial similarities in terms of population characteristics, symptoms, and urodynamic findings. Conclusions: Our study showed a high prevalence of COUB, and a link between this clinical syndrome and DOU was demonstrated. They showed substantial similarities in terms of clinical and urodynamics correlates. Based on these findings, we do think that urodynamic tests can be useful to improve knowledge on COUB and may be of help in the management of this condition. MDPI 2022-09-08 /pmc/articles/PMC9498318/ /pubmed/36141332 http://dx.doi.org/10.3390/healthcare10091720 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Frigerio, Matteo Barba, Marta Marino, Giuseppe Volontè, Silvia Melocchi, Tomaso De Vicari, Desirèe Torella, Marco Salvatore, Stefano Braga, Andrea Serati, Maurizio Manodoro, Stefano Cola, Alice Coexistent Detrusor Overactivity-Underactivity in Patients with Pelvic Floor Disorders |
title | Coexistent Detrusor Overactivity-Underactivity in Patients with Pelvic Floor Disorders |
title_full | Coexistent Detrusor Overactivity-Underactivity in Patients with Pelvic Floor Disorders |
title_fullStr | Coexistent Detrusor Overactivity-Underactivity in Patients with Pelvic Floor Disorders |
title_full_unstemmed | Coexistent Detrusor Overactivity-Underactivity in Patients with Pelvic Floor Disorders |
title_short | Coexistent Detrusor Overactivity-Underactivity in Patients with Pelvic Floor Disorders |
title_sort | coexistent detrusor overactivity-underactivity in patients with pelvic floor disorders |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9498318/ https://www.ncbi.nlm.nih.gov/pubmed/36141332 http://dx.doi.org/10.3390/healthcare10091720 |
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