Transgenic Expression of Nrf2 Induces a Pro-Reductive Stress and Adaptive Cardiac Remodeling in the Mouse

Nuclear factor, erythroid 2 like 2 (Nfe2l2 or Nrf2), is a transcription factor that protects cells by maintaining a homeostatic redox state during stress. The constitutive expression of Nrf2 (CaNrf2-TG) was previously shown to be pathological to the heart over time. We tested a hypothesis that the c...

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Detalles Bibliográficos
Autores principales: Jyothidasan, Arun, Sunny, Sini, Murugesan, Saravanakumar, Quiles, Justin M., Challa, Anil Kumar, Dalley, Brian, Cinghu, Senthil Kumar, Nanda, Vivek, Rajasekaran, Namakkal-Soorappan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9498410/
https://www.ncbi.nlm.nih.gov/pubmed/36140682
http://dx.doi.org/10.3390/genes13091514

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9498410/
https://www.ncbi.nlm.nih.gov/pubmed/36140682
http://dx.doi.org/10.3390/genes13091514

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