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A thermodynamically consistent monte carlo cross-bridge model with a trapping mechanism reveals the role of stretch activation in heart pumping
Changes in intracellular calcium concentrations regulate heart beats. However, the decline in the left ventricular pressure during early diastole is much sharper than that of the Ca(2+) transient, resulting in a rapid supply of blood to the left ventricle during the diastole. At the tissue level, ca...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9498833/ https://www.ncbi.nlm.nih.gov/pubmed/36160842 http://dx.doi.org/10.3389/fphys.2022.855303 |