DNA Polymerase ζ without the C-Terminus of Catalytic Subunit Rev3 Retains Characteristic Activity, but Alters Mutation Specificity of Ultraviolet Radiation in Yeast

DNA polymerase ζ (pol ζ) plays a central role in replicating damaged genomic DNA. When DNA synthesis stalls at a lesion, it participates in translesion DNA synthesis (TLS), which helps replication proceed. TLS prevents cell death at the expense of new mutations. The current model indicates that pol...

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Detalles Bibliográficos
Autores principales: Siebler, Hollie M., Cui, Jian, Hill, Sarah E., Pavlov, Youri I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9498848/
https://www.ncbi.nlm.nih.gov/pubmed/36140745
http://dx.doi.org/10.3390/genes13091576

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9498848/
https://www.ncbi.nlm.nih.gov/pubmed/36140745
http://dx.doi.org/10.3390/genes13091576

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