Cargando…
Seasonal changes in proportion of cardiac surgeries associated with diabetes, smoking and elderly age
BACKGROUND: Seasonal variations in the ambient temperature may affect the exacerbation of cardiovascular diseases. Our primary objective was to evaluate the seasonality of the monthly proportion of cardiac surgeries associated with diabetes, smoking and/or elderly age at a tertiary-care university h...
Autores principales: | , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9498963/ https://www.ncbi.nlm.nih.gov/pubmed/36136994 http://dx.doi.org/10.1371/journal.pone.0274105 |
_version_ | 1784794891160649728 |
---|---|
author | Peták, Ferenc Kovács, Barbara N. Agócs, Szilvia Virág, Katalin Nyári, Tibor Molnár, Andrea Südy, Roberta Lengyel, Csaba Babik, Barna |
author_facet | Peták, Ferenc Kovács, Barbara N. Agócs, Szilvia Virág, Katalin Nyári, Tibor Molnár, Andrea Südy, Roberta Lengyel, Csaba Babik, Barna |
author_sort | Peták, Ferenc |
collection | PubMed |
description | BACKGROUND: Seasonal variations in the ambient temperature may affect the exacerbation of cardiovascular diseases. Our primary objective was to evaluate the seasonality of the monthly proportion of cardiac surgeries associated with diabetes, smoking and/or elderly age at a tertiary-care university hospital in East-Central Europe with a temperate climate zone. As a secondary objective, we also assessed whether additional factors affecting small blood vessels (smoking, aging, obesity) modulate the seasonal variability of diabetes. METHODS: Medical records were analyzed for 9838 consecutive adult patients who underwent cardiac surgery in 2007–2018. Individual seasonal variations of diabetes, smoking, and elderly patients were analyzed monthly, along with the potential risk factors for cardiovascular complication. We also characterized whether pairwise coexistence of diabetes, smoking, and elderly age augments or blunts the seasonal variations. RESULTS: Seasonal variations in the monthly proportion of cardiac surgeries associated with diabetes, smoking and/or elderly age were observed. The proportion of cardiac surgeries of non-elderly and smoking patients with diabetes peaked in winter (amplitude of change as [peak-nadir]/nadir: 19.2%, p<0.02), which was associated with increases in systolic (6.1%, p<0.001) and diastolic blood pressures (4.4%, p<0.05) and serum triglyceride levels (27.1%, p<0.005). However, heart surgery in elderly patients without diabetes and smoking was most frequently required in summer (52.1%, p<0.001). Concomitant occurrence of diabetes and smoking had an additive effect on the requirement for cardiac surgery (107%, p<0.001), while the simultaneous presence of older age and diabetes or smoking eliminated seasonal variations. CONCLUSIONS: Scheduling regular cardiovascular control in accordance with periodicities in diabetes, elderly, and smoking patients more than once a year may improve patient health and social consequences. TRIAL REGISTRATION: NCT03967639. |
format | Online Article Text |
id | pubmed-9498963 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-94989632022-09-23 Seasonal changes in proportion of cardiac surgeries associated with diabetes, smoking and elderly age Peták, Ferenc Kovács, Barbara N. Agócs, Szilvia Virág, Katalin Nyári, Tibor Molnár, Andrea Südy, Roberta Lengyel, Csaba Babik, Barna PLoS One Research Article BACKGROUND: Seasonal variations in the ambient temperature may affect the exacerbation of cardiovascular diseases. Our primary objective was to evaluate the seasonality of the monthly proportion of cardiac surgeries associated with diabetes, smoking and/or elderly age at a tertiary-care university hospital in East-Central Europe with a temperate climate zone. As a secondary objective, we also assessed whether additional factors affecting small blood vessels (smoking, aging, obesity) modulate the seasonal variability of diabetes. METHODS: Medical records were analyzed for 9838 consecutive adult patients who underwent cardiac surgery in 2007–2018. Individual seasonal variations of diabetes, smoking, and elderly patients were analyzed monthly, along with the potential risk factors for cardiovascular complication. We also characterized whether pairwise coexistence of diabetes, smoking, and elderly age augments or blunts the seasonal variations. RESULTS: Seasonal variations in the monthly proportion of cardiac surgeries associated with diabetes, smoking and/or elderly age were observed. The proportion of cardiac surgeries of non-elderly and smoking patients with diabetes peaked in winter (amplitude of change as [peak-nadir]/nadir: 19.2%, p<0.02), which was associated with increases in systolic (6.1%, p<0.001) and diastolic blood pressures (4.4%, p<0.05) and serum triglyceride levels (27.1%, p<0.005). However, heart surgery in elderly patients without diabetes and smoking was most frequently required in summer (52.1%, p<0.001). Concomitant occurrence of diabetes and smoking had an additive effect on the requirement for cardiac surgery (107%, p<0.001), while the simultaneous presence of older age and diabetes or smoking eliminated seasonal variations. CONCLUSIONS: Scheduling regular cardiovascular control in accordance with periodicities in diabetes, elderly, and smoking patients more than once a year may improve patient health and social consequences. TRIAL REGISTRATION: NCT03967639. Public Library of Science 2022-09-22 /pmc/articles/PMC9498963/ /pubmed/36136994 http://dx.doi.org/10.1371/journal.pone.0274105 Text en © 2022 Peták et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Peták, Ferenc Kovács, Barbara N. Agócs, Szilvia Virág, Katalin Nyári, Tibor Molnár, Andrea Südy, Roberta Lengyel, Csaba Babik, Barna Seasonal changes in proportion of cardiac surgeries associated with diabetes, smoking and elderly age |
title | Seasonal changes in proportion of cardiac surgeries associated with diabetes, smoking and elderly age |
title_full | Seasonal changes in proportion of cardiac surgeries associated with diabetes, smoking and elderly age |
title_fullStr | Seasonal changes in proportion of cardiac surgeries associated with diabetes, smoking and elderly age |
title_full_unstemmed | Seasonal changes in proportion of cardiac surgeries associated with diabetes, smoking and elderly age |
title_short | Seasonal changes in proportion of cardiac surgeries associated with diabetes, smoking and elderly age |
title_sort | seasonal changes in proportion of cardiac surgeries associated with diabetes, smoking and elderly age |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9498963/ https://www.ncbi.nlm.nih.gov/pubmed/36136994 http://dx.doi.org/10.1371/journal.pone.0274105 |
work_keys_str_mv | AT petakferenc seasonalchangesinproportionofcardiacsurgeriesassociatedwithdiabetessmokingandelderlyage AT kovacsbarbaran seasonalchangesinproportionofcardiacsurgeriesassociatedwithdiabetessmokingandelderlyage AT agocsszilvia seasonalchangesinproportionofcardiacsurgeriesassociatedwithdiabetessmokingandelderlyage AT viragkatalin seasonalchangesinproportionofcardiacsurgeriesassociatedwithdiabetessmokingandelderlyage AT nyaritibor seasonalchangesinproportionofcardiacsurgeriesassociatedwithdiabetessmokingandelderlyage AT molnarandrea seasonalchangesinproportionofcardiacsurgeriesassociatedwithdiabetessmokingandelderlyage AT sudyroberta seasonalchangesinproportionofcardiacsurgeriesassociatedwithdiabetessmokingandelderlyage AT lengyelcsaba seasonalchangesinproportionofcardiacsurgeriesassociatedwithdiabetessmokingandelderlyage AT babikbarna seasonalchangesinproportionofcardiacsurgeriesassociatedwithdiabetessmokingandelderlyage |