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Primary and metastatic tumors exhibit systems-level differences in dependence on mitochondrial respiratory function
The Warburg effect, aerobic glycolysis, is a hallmark feature of cancer cells grown in culture. However, the relative roles of glycolysis and respiratory metabolism in supporting in vivo tumor growth and processes such as tumor dissemination and metastatic growth remain poorly understood, particular...
Autores principales: | Bennett, Neal K., Nakaoka, Hiroki J., Laurent, Danny, Okimoto, Ross A., Sei, Yoshitaka, Horvai, Andrew E., Bivona, Trever G., ten Hoeve, Johanna, Graeber, Thomas G., Nakamura, Ken, Nakamura, Jean L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9498964/ https://www.ncbi.nlm.nih.gov/pubmed/36137002 http://dx.doi.org/10.1371/journal.pbio.3001753 |
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