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T(h)17, T(h)22, and Myeloid-Derived Suppressor Cell Population Dynamics and Response to IL-6 in 4T1 Mammary Carcinoma

Immunotherapies relying on type 1 immunity have shown robust clinical responses in some cancers yet remain relatively ineffective in solid breast tumors. Polarization toward type 2 immunity and expansion of myeloid-derived suppressor cells (MDSC) confer resistance to therapy, though it remains uncle...

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Detalles Bibliográficos
Autores principales: Rasé, Viva J., Hayward, Reid, Haughian, James M., Pullen, Nicholas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9498998/
https://www.ncbi.nlm.nih.gov/pubmed/36142210
http://dx.doi.org/10.3390/ijms231810299