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Impact of G-Quadruplex Structures on Methylation of Model Substrates by DNA Methyltransferase Dnmt3a

In mammals, de novo methylation of cytosines in DNA CpG sites is performed by DNA methyltransferase Dnmt3a. Changes in the methylation status of CpG islands are critical for gene regulation and for the progression of some cancers. Recently, the potential involvement of DNA G-quadruplexes (G4s) in me...

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Detalles Bibliográficos
Autores principales:	Loiko, Andrei G., Sergeev, Alexander V., Genatullina, Adelya I., Monakhova, Mayya V., Kubareva, Elena A., Dolinnaya, Nina G., Gromova, Elizaveta S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499004/ https://www.ncbi.nlm.nih.gov/pubmed/36142137 http://dx.doi.org/10.3390/ijms231810226

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