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Patient-derived monoclonal antibody neutralizes HCV infection in vitro and vivo without generating escape mutants

In recent years, new direct-acting antivirals for hepatitis C virus (HCV) have been approved, but hepatitis C continues to pose a threat to human health. It is important to develop neutralizing anti-HCV antibodies to prevent medical and accidental infection, such as might occur via liver transplanta...

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Detalles Bibliográficos
Autores principales:	Yokokawa, Hiroshi, Shinohara, Midori, Teraoka, Yuji, Imamura, Michio, Nakamura, Noriko, Watanabe, Noriyuki, Date, Tomoko, Aizaki, Hideki, Iwamura, Tomokatsu, Narumi, Hideki, Chayama, Kazuaki, Wakita, Takaji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499215/ https://www.ncbi.nlm.nih.gov/pubmed/36137152 http://dx.doi.org/10.1371/journal.pone.0274283

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