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Aldehyde Dehydrogenase 2 Activator Augments the Beneficial Effects of Empagliflozin in Mice with Diabetes-Associated HFpEF

To ameliorate diabetes mellitus-associated heart failure with preserved ejection fraction (HFpEF), we plan to lower diabetes-mediated oxidative stress-induced 4-hydroxy-2-nonenal (4HNE) accumulation by pharmacological agents that either decrease 4HNE generation or increase its detoxification.A cellu...

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Detalles Bibliográficos
Autores principales:	Pan, Guodong, Roy, Bipradas, Giri, Shailendra, Lanfear, David E., Thandavarayan, Rajarajan A., Guha, Ashrith, Ortiz, Pablo A., Palaniyandi, Suresh Selvaraj
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499333/ https://www.ncbi.nlm.nih.gov/pubmed/36142350 http://dx.doi.org/10.3390/ijms231810439

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