Down-Regulation of Double C2 Domain Alpha Promotes the Formation of Hyperplastic Nerve Fibers in Aganglionic Segments of Hirschsprung’s Disease

Hirschsprung’s disease (HSCR) is a common developmental anomaly of the gastrointestinal tract in children. The most significant characteristics of aganglionic segments in HSCR are hyperplastic extrinsic nerve fibers and the absence of endogenous ganglion plexus. Double C2 domain alpha (DOC2A) is mai...

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Detalles Bibliográficos
Autores principales: Xiao, Jun, Meng, Xinyao, Chen, Ke, Wang, Jing, Wu, Luyao, Chen, Yingjian, Yu, Xiaosi, Feng, Jiexiong, Li, Zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499397/
https://www.ncbi.nlm.nih.gov/pubmed/36142117
http://dx.doi.org/10.3390/ijms231810204

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499397/
https://www.ncbi.nlm.nih.gov/pubmed/36142117
http://dx.doi.org/10.3390/ijms231810204

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