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Amorphous and Co-Amorphous Olanzapine Stability in Formulations Intended for Wet Granulation and Pelletization

The preparation of amorphous and co-amorphous systems (CAMs) effectively addresses the solubility and bioavailability issues of poorly water-soluble chemical entities. However, stress conditions imposed during common pharmaceutical processing (e.g., tableting) may cause the recrystallization of the...

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Detalles Bibliográficos
Autores principales: da Costa, Nuno F., Daniels, Rolf, Fernandes, Ana I., Pinto, João F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499418/
https://www.ncbi.nlm.nih.gov/pubmed/36142179
http://dx.doi.org/10.3390/ijms231810234