Potent Chlorambucil-Platinum(IV) Prodrugs

The DNA-alkylating derivative chlorambucil was coordinated in the axial position to atypical cytotoxic, heterocyclic, and non-DNA coordinating platinum(IV) complexes of type, [Pt(IV)(H(L))(A(L))(OH)(2)](NO(3))(2) (where H(L) is 1,10-phenanthroline, 5-methyl-1,10-phenanthroline or 5,6-dimethyl-1,10-p...

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Detalles Bibliográficos
Autores principales: Aputen, Angelico D., Elias, Maria George, Gilbert, Jayne, Sakoff, Jennette A., Gordon, Christopher P., Scott, Kieran F., Aldrich-Wright, Janice R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499463/
https://www.ncbi.nlm.nih.gov/pubmed/36142383
http://dx.doi.org/10.3390/ijms231810471

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499463/
https://www.ncbi.nlm.nih.gov/pubmed/36142383
http://dx.doi.org/10.3390/ijms231810471

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