Novel Planar Pt(II) Cyclometallated Cytotoxic Complexes with G-Quadruplex Stabilisation and Luminescent Properties

Herein is described the development of a series of novel quadruplex DNA (QDNA)-stabilising cyclometallated square–planar metal complexes (CMCs). Melting experiments using quadruplex DNA (QDNA) demonstrated that interactions with the complexes increased the melting temperature by up to 19 °C. This QD...

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Detalles Bibliográficos
Autores principales: McGhie, Brondwyn S., Sakoff, Jennette, Gilbert, Jayne, Gordon, Christopher P., Aldrich-Wright, Janice R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499473/
https://www.ncbi.nlm.nih.gov/pubmed/36142379
http://dx.doi.org/10.3390/ijms231810469

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499473/
https://www.ncbi.nlm.nih.gov/pubmed/36142379
http://dx.doi.org/10.3390/ijms231810469

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