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Novel Planar Pt(II) Cyclometallated Cytotoxic Complexes with G-Quadruplex Stabilisation and Luminescent Properties
Herein is described the development of a series of novel quadruplex DNA (QDNA)-stabilising cyclometallated square–planar metal complexes (CMCs). Melting experiments using quadruplex DNA (QDNA) demonstrated that interactions with the complexes increased the melting temperature by up to 19 °C. This QD...
Autores principales: | McGhie, Brondwyn S., Sakoff, Jennette, Gilbert, Jayne, Gordon, Christopher P., Aldrich-Wright, Janice R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499473/ https://www.ncbi.nlm.nih.gov/pubmed/36142379 http://dx.doi.org/10.3390/ijms231810469 |
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