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Clomifene and Assisted Reproductive Technology in Humans Are Associated with Sex-Specific Offspring Epigenetic Alterations in Imprinted Control Regions

Children conceived with assisted reproductive technology (ART) have an increased risk of adverse outcomes, including congenital malformations and imprinted gene disorders. In a retrospective North Carolina-based-birth-cohort, we examined the effect of ovulation drugs and ART on CpG methylation in di...

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Detalles Bibliográficos
Autores principales: Lloyd, Dillon T., Skinner, Harlyn G., Maguire, Rachel, Murphy, Susan K., Motsinger-Reif, Alison A., Hoyo, Cathrine, House, John S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499479/
https://www.ncbi.nlm.nih.gov/pubmed/36142363
http://dx.doi.org/10.3390/ijms231810450

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