Structure of IMPORTIN-4 bound to the H3–H4–ASF1 histone–histone chaperone complex

IMPORTIN-4, the primary nuclear import receptor of core histones H3 and H4, binds the H3–H4 dimer and histone chaperone ASF1 prior to nuclear import. However, how H3–H3–ASF1 is recognized for transport cannot be explained by available crystal structures of IMPORTIN-4–histone tail peptide complexes....

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Detalles Bibliográficos
Autores principales: Bernardes, Natália Elisa, Fung, Ho Yee Joyce, Li, Yang, Chen, Zhe, Chook, Yuh Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499513/
https://www.ncbi.nlm.nih.gov/pubmed/36103578
http://dx.doi.org/10.1073/pnas.2207177119

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