Recurrent emergence of Klebsiella pneumoniae carbapenem resistance mediated by an inhibitory ompK36 mRNA secondary structure

Outer membrane porins in Gram-negative bacteria facilitate antibiotic influx. In Klebsiella pneumoniae, modifications in the porin OmpK36 are implicated in increasing resistance to carbapenems. An analysis of large K. pneumoniae genome collections, encompassing major healthcare-associated clones, re...

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Detalles Bibliográficos
Autores principales: Wong, Joshua L. C., David, Sophia, Sanchez-Garrido, Julia, Woo, Jia Z., Low, Wen Wen, Morecchiato, Fabio, Giani, Tommaso, Rossolini, Gian Maria, Beis, Konstantinos, Brett, Stephen J., Clements, Abigail, Aanensen, David M., Rouskin, Silvi, Frankel, Gad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499542/
https://www.ncbi.nlm.nih.gov/pubmed/36095213
http://dx.doi.org/10.1073/pnas.2203593119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499542/
https://www.ncbi.nlm.nih.gov/pubmed/36095213
http://dx.doi.org/10.1073/pnas.2203593119

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