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Strategies for Therapeutic Amelioration of Aberrant Plasma Zn(2+) Handling in Thrombotic Disease: Targeting Fatty Acid/Serum Albumin-Mediated Effects

The initiation, maintenance and regulation of blood coagulation is inexorably linked to the actions of Zn(2+) in blood plasma. Zn(2+) interacts with a variety of haemostatic proteins in the bloodstream including fibrinogen, histidine-rich glycoprotein (HRG) and high molecular weight kininogen (HMWK)...

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Detalles Bibliográficos
Autores principales: Regan-Smith, Spencer, Fritzen, Remi, Hierons, Stephen J., Ajjan, Ramzi A., Blindauer, Claudia A., Stewart, Alan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499645/
https://www.ncbi.nlm.nih.gov/pubmed/36142215
http://dx.doi.org/10.3390/ijms231810302