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Trophoblast Exosomal UCA1 Induces Endothelial Injury through the PFN1-RhoA/ROCK Pathway in Preeclampsia: A Human-Specific Adaptive Pathogenic Mechanism

Preeclampsia is regarded as an evolution-related disease that has only been observed in humans and our closest relatives, and the important factor contributing to its pathogenesis is endothelial dysregulation secondary to a stressed placenta. Hypoxia-inducible factor 1 subunit alpha (HIF1α), a highl...

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Detalles Bibliográficos
Autores principales:	Wu, Suwen, Cui, Yutong, Zhao, Huanqiang, Xiao, Xirong, Gong, Lili, Xu, Huangfang, Zhou, Qiongjie, Ma, Duan, Li, Xiaotian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499815/ https://www.ncbi.nlm.nih.gov/pubmed/36160709 http://dx.doi.org/10.1155/2022/2198923

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