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Viral proteases activate the CARD8 inflammasome in the human cardiovascular system

Nucleotide-binding oligomerization domain (NBD), leucine-rich repeat (LRR) containing protein family (NLRs) are intracellular pattern recognition receptors that mediate innate immunity against infections. The endothelium is the first line of defense against blood-borne pathogens, but it is unclear w...

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Detalles Bibliográficos
Autores principales: Nadkarni, Rhea, Chu, Wern Cui, Lee, Cheryl Q.E., Mohamud, Yasir, Yap, Lynn, Toh, Gee Ann, Beh, Sheryl, Lim, Radiance, Fan, Yiyun Michelle, Zhang, Yizhuo Lyanne, Robinson, Kim, Tryggvason, Karl, Luo, Honglin, Zhong, Franklin, Ho, Lena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499823/
https://www.ncbi.nlm.nih.gov/pubmed/36129453
http://dx.doi.org/10.1084/jem.20212117