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Viral proteases activate the CARD8 inflammasome in the human cardiovascular system
Nucleotide-binding oligomerization domain (NBD), leucine-rich repeat (LRR) containing protein family (NLRs) are intracellular pattern recognition receptors that mediate innate immunity against infections. The endothelium is the first line of defense against blood-borne pathogens, but it is unclear w...
Autores principales: | Nadkarni, Rhea, Chu, Wern Cui, Lee, Cheryl Q.E., Mohamud, Yasir, Yap, Lynn, Toh, Gee Ann, Beh, Sheryl, Lim, Radiance, Fan, Yiyun Michelle, Zhang, Yizhuo Lyanne, Robinson, Kim, Tryggvason, Karl, Luo, Honglin, Zhong, Franklin, Ho, Lena |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499823/ https://www.ncbi.nlm.nih.gov/pubmed/36129453 http://dx.doi.org/10.1084/jem.20212117 |
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