The low-density lipoprotein receptor–mTORC1 axis coordinates CD8(+) T cell activation

Activation of T cells relies on the availability of intracellular cholesterol for an effective response after stimulation. We investigated the contribution of cholesterol derived from extracellular uptake by the low-density lipoprotein (LDL) receptor in the immunometabolic response of T cells. By co...

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Detalles Bibliográficos
Autores principales: Bonacina, Fabrizia, Moregola, Annalisa, Svecla, Monika, Coe, David, Uboldi, Patrizia, Fraire, Sara, Beretta, Simona, Beretta, Giangiacomo, Pellegatta, Fabio, Catapano, Alberico Luigi, Marelli-Berg, Federica M., Norata, Giuseppe Danilo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499829/
https://www.ncbi.nlm.nih.gov/pubmed/36129440
http://dx.doi.org/10.1083/jcb.202202011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499829/
https://www.ncbi.nlm.nih.gov/pubmed/36129440
http://dx.doi.org/10.1083/jcb.202202011

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