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The low-density lipoprotein receptor–mTORC1 axis coordinates CD8(+) T cell activation

Activation of T cells relies on the availability of intracellular cholesterol for an effective response after stimulation. We investigated the contribution of cholesterol derived from extracellular uptake by the low-density lipoprotein (LDL) receptor in the immunometabolic response of T cells. By co...

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Detalles Bibliográficos
Autores principales:	Bonacina, Fabrizia, Moregola, Annalisa, Svecla, Monika, Coe, David, Uboldi, Patrizia, Fraire, Sara, Beretta, Simona, Beretta, Giangiacomo, Pellegatta, Fabio, Catapano, Alberico Luigi, Marelli-Berg, Federica M., Norata, Giuseppe Danilo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499829/ https://www.ncbi.nlm.nih.gov/pubmed/36129440 http://dx.doi.org/10.1083/jcb.202202011

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