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Glimepiride mitigates tauopathy and neuroinflammation in P301S transgenic mice: role of AKT/GSK3β signaling

BACKGROUND AND OBJECTIVE: Tauopathy is a group of neurodegenerative diseases in which the pathogenesis processes are related to tau protein. The imbalances between the activities of kinases and phosphatases of tau protein lead to tau hyperphosphorylation and subsequent neurodegeneration. Numerous st...

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Detalles Bibliográficos
Autores principales:	Zaki, Mennatallah O., El-Desouky, S., Elsherbiny, Doaa A., Salama, Mohamed, Azab, Samar S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499917/ https://www.ncbi.nlm.nih.gov/pubmed/35922737 http://dx.doi.org/10.1007/s10787-022-01023-w

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