A chemical method for generating live-attenuated, replication-defective DNA viruses for vaccine development

The development of a chemically attenuated, replication-incompetent virus vaccine can provide protection against diseases caused by DNA viruses. In this study, we have developed a method to produce live-attenuated, replication-defective viruses using centanamycin (CM), a chemical compound that alkyl...

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Detalles Bibliográficos
Autores principales: Jaijyan, Dabbu Kumar, Govindasamy, Kavitha, Lee, Moses, Zhu, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499982/
https://www.ncbi.nlm.nih.gov/pubmed/36160049
http://dx.doi.org/10.1016/j.crmeth.2022.100287

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499982/
https://www.ncbi.nlm.nih.gov/pubmed/36160049
http://dx.doi.org/10.1016/j.crmeth.2022.100287

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