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A chemical method for generating live-attenuated, replication-defective DNA viruses for vaccine development
The development of a chemically attenuated, replication-incompetent virus vaccine can provide protection against diseases caused by DNA viruses. In this study, we have developed a method to produce live-attenuated, replication-defective viruses using centanamycin (CM), a chemical compound that alkyl...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499982/ https://www.ncbi.nlm.nih.gov/pubmed/36160049 http://dx.doi.org/10.1016/j.crmeth.2022.100287 |