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Sensitive and reproducible cell-free methylome quantification with synthetic spike-in controls

Cell-free methylated DNA immunoprecipitation sequencing (cfMeDIP-seq) identifies genomic regions with DNA methylation, using a protocol adapted to work with low-input DNA samples and with cell-free DNA (cfDNA). We developed a set of synthetic spike-in DNA controls for cfMeDIP-seq to provide a simple...

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Detalles Bibliográficos
Autores principales:	Wilson, Samantha L., Shen, Shu Yi, Harmon, Lauren, Burgener, Justin M., Triche, Tim, Bratman, Scott V., De Carvalho, Daniel D., Hoffman, Michael M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499995/ https://www.ncbi.nlm.nih.gov/pubmed/36160046 http://dx.doi.org/10.1016/j.crmeth.2022.100294

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