Robust genome editing via modRNA-based Cas9 or base editor in human pluripotent stem cells

CRISPR systems have revolutionized biomedical research because they offer an unprecedented opportunity for genome editing. However, a bottleneck of applying CRISPR systems in human pluripotent stem cells (hPSCs) is how to deliver CRISPR effectors easily and efficiently. Here, we developed modified m...

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Detalles Bibliográficos
Autores principales: Haideri, Tahir, Howells, Alessandro, Jiang, Yuqian, Yang, Jian, Bao, Xiaoping, Lian, Xiaojun Lance
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499999/
https://www.ncbi.nlm.nih.gov/pubmed/36160051
http://dx.doi.org/10.1016/j.crmeth.2022.100290

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9499999/
https://www.ncbi.nlm.nih.gov/pubmed/36160051
http://dx.doi.org/10.1016/j.crmeth.2022.100290

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