Deep-learning analysis of micropattern-based organoids enables high-throughput drug screening of Huntington’s disease models

Organoids are carrying the promise of modeling complex disease phenotypes and serving as a powerful basis for unbiased drug screens, potentially offering a more efficient drug-discovery route. However, unsolved technical bottlenecks of reproducibility and scalability have prevented the use of curren...

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Detalles Bibliográficos
Autores principales: Metzger, Jakob J., Pereda, Carlota, Adhikari, Arjun, Haremaki, Tomomi, Galgoczi, Szilvia, Siggia, Eric D., Brivanlou, Ali H., Etoc, Fred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9500000/
https://www.ncbi.nlm.nih.gov/pubmed/36160045
http://dx.doi.org/10.1016/j.crmeth.2022.100297

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9500000/
https://www.ncbi.nlm.nih.gov/pubmed/36160045
http://dx.doi.org/10.1016/j.crmeth.2022.100297

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