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Protein condensation diseases: therapeutic opportunities
Condensed states of proteins, including liquid-like membraneless organelles and solid-like aggregates, contribute in fundamental ways to the organisation and function of the cell. Perturbations of these states can lead to a variety of diseases through mechanisms that we are now beginning to understa...
Autores principales: | Vendruscolo, Michele, Fuxreiter, Monika |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9500012/ https://www.ncbi.nlm.nih.gov/pubmed/36138006 http://dx.doi.org/10.1038/s41467-022-32940-7 |
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