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Patient-specific numerical investigation of the correction of cervical kyphotic deformity based on a retrospective clinical case

Little research has been reported on evaluating the safety of the fixation construct in cervical kyphosis correction. In this study, we proposed a principal-strain criterion to evaluate the safety of the fixation construct and validated the modeling method against a retrospective case of anterior ce...

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Autores principales: Wu, Tianchi, Chen, Hongyu, Sun, Yu, Xia, Tian, Zhou, Feifei, Lu, William W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9500315/
https://www.ncbi.nlm.nih.gov/pubmed/36159686
http://dx.doi.org/10.3389/fbioe.2022.950839
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author Wu, Tianchi
Chen, Hongyu
Sun, Yu
Xia, Tian
Zhou, Feifei
Lu, William W.
author_facet Wu, Tianchi
Chen, Hongyu
Sun, Yu
Xia, Tian
Zhou, Feifei
Lu, William W.
author_sort Wu, Tianchi
collection PubMed
description Little research has been reported on evaluating the safety of the fixation construct in cervical kyphosis correction. In this study, we proposed a principal-strain criterion to evaluate the safety of the fixation construct and validated the modeling method against a retrospective case of anterior cervical discectomy fusion (ACDF). From C2 to T2 vertebra bodies, fixation instruments were reconstructed and positioned as per postoperative computed tomography (CT) scans. Head weight (HW) and various moments estimated from isometric strength data were imposed onto the C2. The postoperative stability of non-surgical segments, deformations surrounding the screw trajectories, and contact slipping on zygapophysial joints were analyzed. The model was validated against the reality that the patient had a good fusion and deformity correction. The ACDF restricted the range of motions (ROMs) of cervical segments and lent stability to vertebra fusion, no failure was found in the finite element (FE) model of cervical vertebrae. The deformation surrounding the screw trajectories were concentrated to the lateral sides of trajectories, recommending that the shape of the anterior cervical plate conforming to the curvature of the vertebra and screws fully inserted into vertebrae reduced the deformation concentration around the screw trajectories.
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spelling pubmed-95003152022-09-24 Patient-specific numerical investigation of the correction of cervical kyphotic deformity based on a retrospective clinical case Wu, Tianchi Chen, Hongyu Sun, Yu Xia, Tian Zhou, Feifei Lu, William W. Front Bioeng Biotechnol Bioengineering and Biotechnology Little research has been reported on evaluating the safety of the fixation construct in cervical kyphosis correction. In this study, we proposed a principal-strain criterion to evaluate the safety of the fixation construct and validated the modeling method against a retrospective case of anterior cervical discectomy fusion (ACDF). From C2 to T2 vertebra bodies, fixation instruments were reconstructed and positioned as per postoperative computed tomography (CT) scans. Head weight (HW) and various moments estimated from isometric strength data were imposed onto the C2. The postoperative stability of non-surgical segments, deformations surrounding the screw trajectories, and contact slipping on zygapophysial joints were analyzed. The model was validated against the reality that the patient had a good fusion and deformity correction. The ACDF restricted the range of motions (ROMs) of cervical segments and lent stability to vertebra fusion, no failure was found in the finite element (FE) model of cervical vertebrae. The deformation surrounding the screw trajectories were concentrated to the lateral sides of trajectories, recommending that the shape of the anterior cervical plate conforming to the curvature of the vertebra and screws fully inserted into vertebrae reduced the deformation concentration around the screw trajectories. Frontiers Media S.A. 2022-09-09 /pmc/articles/PMC9500315/ /pubmed/36159686 http://dx.doi.org/10.3389/fbioe.2022.950839 Text en Copyright © 2022 Wu, Chen, Sun, Xia, Zhou and Lu. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Bioengineering and Biotechnology
Wu, Tianchi
Chen, Hongyu
Sun, Yu
Xia, Tian
Zhou, Feifei
Lu, William W.
Patient-specific numerical investigation of the correction of cervical kyphotic deformity based on a retrospective clinical case
title Patient-specific numerical investigation of the correction of cervical kyphotic deformity based on a retrospective clinical case
title_full Patient-specific numerical investigation of the correction of cervical kyphotic deformity based on a retrospective clinical case
title_fullStr Patient-specific numerical investigation of the correction of cervical kyphotic deformity based on a retrospective clinical case
title_full_unstemmed Patient-specific numerical investigation of the correction of cervical kyphotic deformity based on a retrospective clinical case
title_short Patient-specific numerical investigation of the correction of cervical kyphotic deformity based on a retrospective clinical case
title_sort patient-specific numerical investigation of the correction of cervical kyphotic deformity based on a retrospective clinical case
topic Bioengineering and Biotechnology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9500315/
https://www.ncbi.nlm.nih.gov/pubmed/36159686
http://dx.doi.org/10.3389/fbioe.2022.950839
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