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A specific immune signature for predicting the prognosis of glioma patients with IDH1-mutation and guiding immune checkpoint blockade therapy

Isocitrate dehydrogenase (IDH1) is frequently mutated in glioma tissues, and this mutation mediates specific tumor-promoting mechanisms in glioma cells. We aimed to identify specific immune biomarkers for IDH1-mutation (IDH1mt) glioma. The Cancer Genome Atlas (TCGA) and Chinese Glioma Genome Atlas (...

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Detalles Bibliográficos
Autores principales:	Zeng, Zhirui, Hu, Chujiao, Ruan, Wanyuan, Zhang, Jinjuan, Lei, Shan, Yang, Yushi, Peng, Pailan, Pan, Feng, Chen, Tengxiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9500319/ https://www.ncbi.nlm.nih.gov/pubmed/36159801 http://dx.doi.org/10.3389/fimmu.2022.1001381

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