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Endogenous TRAIL-R4 critically impacts apoptotic and non-apoptotic TRAIL-induced signaling in cancer cells

Binding of TRAIL to its death domain-containing receptors TRAIL-R1 and TRAIL-R2 can induce cell death and/or pro-inflammatory signaling. The importance of TRAIL and TRAIL-R1/R2 in tumor immune surveillance and cancer biology has meanwhile been well documented. In addition, TRAIL has been shown to pr...

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Detalles Bibliográficos
Autores principales:	Rambow, Anna-Christina, Aschenbach, Insa, Hagelund, Sofie, Tawfik, Doaa, Gundlach, Jan-Paul, Weiße, Sebastian, Maass, Nicolai, Trauzold, Anna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9500463/ https://www.ncbi.nlm.nih.gov/pubmed/36158196 http://dx.doi.org/10.3389/fcell.2022.942718

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