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Preparation and Characterization of Pazopanib Hydrochloride-Loaded Four-Component Self-Nanoemulsifying Drug Delivery Systems Preconcentrate for Enhanced Solubility and Dissolution

The aim of this study was to develop a four-component self-nanoemulsifying drug delivery system (FCS) to enhance the solubility and dissolution of pazopanib hydrochloride (PZH). In the solubility test, PZH showed a highly pH-dependent solubility (pH 1.2 > water >> pH 4.0 and pH 6.8) and was...

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Detalles Bibliográficos
Autores principales:	Choi, Seung Ah, Park, Eun Ji, Lee, Jun Hak, Min, Kyoung Ah, Kim, Sung Tae, Jang, Dong-Jin, Maeng, Han-Joo, Jin, Sung Giu, Cho, Kwan Hyung
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9500606/ https://www.ncbi.nlm.nih.gov/pubmed/36145623 http://dx.doi.org/10.3390/pharmaceutics14091875

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