Cargando…

Protein Succinylation and Malonylation as Potential Biomarkers in Schizophrenia

Two protein post-translational modifications, lysine succinylation and malonylation, are implicated in protein regulation, glycolysis, and energy metabolism. The precursors of these modifications, succinyl-CoA and malonyl-CoA, are key players in central metabolic processes. Both modification profile...

Descripción completa

Detalles Bibliográficos
Autores principales:	Smith, Bradley Joseph, Brandão-Teles, Caroline, Zuccoli, Giuliana S., Reis-de-Oliveira, Guilherme, Fioramonte, Mariana, Saia-Cereda, Verônica M., Martins-de-Souza, Daniel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9500613/ https://www.ncbi.nlm.nih.gov/pubmed/36143193 http://dx.doi.org/10.3390/jpm12091408

Ejemplares similares

Proteomic signatures of schizophrenia-sourced iPSC-derived neural cells and brain organoids are similar to patients' postmortem brains
por: Nascimento, Juliana Minardi, et al.
Publicado: (2022)

The Energy Metabolism Dysfunction in Psychiatric Disorders Postmortem Brains: Focus on Proteomic Evidence
por: Zuccoli, Giuliana S., et al.
Publicado: (2017)

32.3 MAGNIFYING THE PROTEOME OF SCHIZOPHRENIA BRAINS
por: Fioramonte, Mariana, et al.
Publicado: (2018)

10.1 STEM CELL-DERIVED IN VITRO MODELS FOR DEPICTING THE ROLE OF GLIA IN SCHIZOPHRENIA FROM A PROTEOMIC PERSPECTIVE
por: Nascimento, Juliana, et al.
Publicado: (2018)

Malonyl-proteome profiles of Staphylococcus aureus reveal lysine malonylation modification in enzymes involved in energy metabolism
por: Shi, Yanan, et al.
Publicado: (2021)

Malonylation of GAPDH is an inflammatory signal in macrophages
por: Galván-Peña, Silvia, et al.
Publicado: (2019)

The acyltransferase PMAT1 malonylates brassinolide glucoside
por: Gan, Sufu, et al.
Publicado: (2021)

Systematic analysis of lysine malonylation in Streptococcus mutans
por: Li, Zhengyi, et al.
Publicado: (2022)

Lysine Malonylation and Its Links to Metabolism and Diseases
por: Zou, Lu, et al.
Publicado: (2023)

Mal-Prec: computational prediction of protein Malonylation sites via machine learning based feature integration: Malonylation site prediction
por: Liu, Xin, et al.
Publicado: (2020)

Supramolecular assembly of KAT2A with succinyl-CoA for histone succinylation
por: Wang, Yugang, et al.
Publicado: (2018)

Global Proteomic Analysis of Lysine Malonylation in Toxoplasma gondii
por: Nie, Lan-Bi, et al.
Publicado: (2020)

Novel Treatment Strategies Targeting Myelin and Oligodendrocyte Dysfunction in Schizophrenia
por: Gouvêa-Junqueira, Danielle, et al.
Publicado: (2020)

M177. THE PROTEOME OF OLIGODENDROCYTES DIFFERENTIATED FROM NEURAL STEM CELL DERIVED FROM SCHIZOPHRENIA PATIENTS
por: Teles Rodrigues, Caroline, et al.
Publicado: (2020)

The Penicillium brasilianum Histone Deacetylase Clr3 Regulates Secondary Metabolite Production and Tolerance to Oxidative Stress
por: Akiyama, Daniel Yuri, et al.
Publicado: (2022)

Biochemical Analysis of Histone Succinylation
por: Yokoyama, Atsushi, et al.
Publicado: (2017)

Nanogels of Succinylated Glycol Chitosan-Succinyl Prednisolone Conjugate: Preparation, In Vitro Characteristics and Therapeutic Potential
por: Zhou, Haiyan, et al.
Publicado: (2019)

DeepSuccinylSite: a deep learning based approach for protein succinylation site prediction
por: Thapa, Niraj, et al.
Publicado: (2020)

Histone malonylation is regulated by SIRT5 and KAT2A
por: Zhang, Ran, et al.
Publicado: (2023)

Screening Phosphorylation Site Mutations in Yeast Acetyl-CoA Carboxylase Using Malonyl-CoA Sensor to Improve Malonyl-CoA-Derived Product
por: Chen, Xiaoxu, et al.
Publicado: (2018)

Semisynthesis of site-specifically succinylated histone reveals that succinylation regulates nucleosome unwrapping rate and DNA accessibility
por: Jing, Yihang, et al.
Publicado: (2020)

Correction: DeepSuccinylSite: a deep learning based approach for protein succinylation site prediction
por: Thapa, Niraj, et al.
Publicado: (2022)

Enzymatic and metabolic regulation of lysine succinylation
por: Sreedhar, Annapoorna, et al.
Publicado: (2019)

The Mystery of Extramitochondrial Proteins Lysine Succinylation
por: Chinopoulos, Christos
Publicado: (2021)

Histone succinylation and its function on the nucleosome
por: Liu, Jiayi, et al.
Publicado: (2021)

Governing glutaminolysis by regulation of glutaminase succinylation
por: Ma, Qingxia, et al.
Publicado: (2021)

Succinylation and redox status in cancer cells
por: Dai, Xiaofeng, et al.
Publicado: (2022)

A review of the mechanism of succinylation in cancer
por: Lu, Keer, et al.
Publicado: (2022)

Chemical-genetic induction of Malonyl-CoA decarboxylase in skeletal muscle
por: Rodriguez, Susana, et al.
Publicado: (2014)

A Malonyl-Based Scaffold for Conjugatable Multivalent Carbohydrate-BODIPY Presentations
por: Uriel, Clara, et al.
Publicado: (2019)

A hybrid feature extraction scheme for efficient malonylation site prediction
por: Sorkhi, Ali Ghanbari, et al.
Publicado: (2022)

Nanogels of a Succinylated Glycol Chitosan-Succinyl Prednisolone Conjugate: Release Behavior, Gastrointestinal Distribution, and Systemic Absorption
por: Zhou, Haiyan, et al.
Publicado: (2020)

First analyses of lysine succinylation proteome and overlap between succinylation and acetylation in Solenopsis invicta Buren (Hymenoptera: Formicidae)
por: Ye, Jingwen, et al.
Publicado: (2022)

Succinyl-proteome profiling of Dendrobium officinale, an important traditional Chinese orchid herb, revealed involvement of succinylation in the glycolysis pathway
por: Feng, Shangguo, et al.
Publicado: (2017)

A Fluorescent, Reagentless Biosensor for ATP, Based on Malonyl-Coenzyme A Synthetase
por: Vancraenenbroeck, Renée, et al.
Publicado: (2015)

Incorporating hybrid models into lysine malonylation sites prediction on mammalian and plant proteins
por: Chung, Chia-Ru, et al.
Publicado: (2020)

Global Identification and Systematic Analysis of Lysine Malonylation in Maize (Zea mays L.)
por: Xu, Min, et al.
Publicado: (2021)

Protein succinylation associated with the progress of hepatocellular carcinoma
por: Bai, Wenhui, et al.
Publicado: (2022)

The emerging role of lysine succinylation in ovarian aging
por: Le, Meiling, et al.
Publicado: (2023)

Malonyl-CoA is a conserved endogenous ATP-competitive mTORC1 inhibitor
por: Nicastro, Raffaele, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_kqcl9610olgusb925ieuk1hm2f