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The Influence of Graphene Content on the Antibacterial Properties of Polycaprolactone
This work contains an analysis of the impact of modifying a bioresorbable polymer—polycaprolactone (PCL)—with various additives on its antibacterial properties. To this end, samples of PCL filament containing various content levels of graphene (GNP), 0.5%, 5%, 10%, were obtained using injection mold...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9500631/ https://www.ncbi.nlm.nih.gov/pubmed/36142811 http://dx.doi.org/10.3390/ijms231810899 |
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author | Hajduga, Maciej B. Bobinski, Rafał Dutka, Mieczysław Bujok, Jan Cwiertnia, Michał Pajak, Celina Kurowska, Anna Rajzer, Izabella |
author_facet | Hajduga, Maciej B. Bobinski, Rafał Dutka, Mieczysław Bujok, Jan Cwiertnia, Michał Pajak, Celina Kurowska, Anna Rajzer, Izabella |
author_sort | Hajduga, Maciej B. |
collection | PubMed |
description | This work contains an analysis of the impact of modifying a bioresorbable polymer—polycaprolactone (PCL)—with various additives on its antibacterial properties. To this end, samples of PCL filament containing various content levels of graphene (GNP), 0.5%, 5%, 10%, were obtained using injection molding. Polymer samples without additives were used for comparison. The next step was to assess the antimicrobial impact of the preparations under study against the following microorganisms: Staphylococcus aureus ATCC 25293, Escherichia coli ATCC 25922, Candida albicans ATCC 10231. Effective bactericidal activity of PCL with small amount of GNP, especially against C. albicans and S. aureus was confirmed. A decrease in this property or even multiplication of microorganisms was observed in direct proportion to the graphene content in the samples. |
format | Online Article Text |
id | pubmed-9500631 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-95006312022-09-24 The Influence of Graphene Content on the Antibacterial Properties of Polycaprolactone Hajduga, Maciej B. Bobinski, Rafał Dutka, Mieczysław Bujok, Jan Cwiertnia, Michał Pajak, Celina Kurowska, Anna Rajzer, Izabella Int J Mol Sci Article This work contains an analysis of the impact of modifying a bioresorbable polymer—polycaprolactone (PCL)—with various additives on its antibacterial properties. To this end, samples of PCL filament containing various content levels of graphene (GNP), 0.5%, 5%, 10%, were obtained using injection molding. Polymer samples without additives were used for comparison. The next step was to assess the antimicrobial impact of the preparations under study against the following microorganisms: Staphylococcus aureus ATCC 25293, Escherichia coli ATCC 25922, Candida albicans ATCC 10231. Effective bactericidal activity of PCL with small amount of GNP, especially against C. albicans and S. aureus was confirmed. A decrease in this property or even multiplication of microorganisms was observed in direct proportion to the graphene content in the samples. MDPI 2022-09-17 /pmc/articles/PMC9500631/ /pubmed/36142811 http://dx.doi.org/10.3390/ijms231810899 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Hajduga, Maciej B. Bobinski, Rafał Dutka, Mieczysław Bujok, Jan Cwiertnia, Michał Pajak, Celina Kurowska, Anna Rajzer, Izabella The Influence of Graphene Content on the Antibacterial Properties of Polycaprolactone |
title | The Influence of Graphene Content on the Antibacterial Properties of Polycaprolactone |
title_full | The Influence of Graphene Content on the Antibacterial Properties of Polycaprolactone |
title_fullStr | The Influence of Graphene Content on the Antibacterial Properties of Polycaprolactone |
title_full_unstemmed | The Influence of Graphene Content on the Antibacterial Properties of Polycaprolactone |
title_short | The Influence of Graphene Content on the Antibacterial Properties of Polycaprolactone |
title_sort | influence of graphene content on the antibacterial properties of polycaprolactone |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9500631/ https://www.ncbi.nlm.nih.gov/pubmed/36142811 http://dx.doi.org/10.3390/ijms231810899 |
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