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The Influence of Graphene Content on the Antibacterial Properties of Polycaprolactone

This work contains an analysis of the impact of modifying a bioresorbable polymer—polycaprolactone (PCL)—with various additives on its antibacterial properties. To this end, samples of PCL filament containing various content levels of graphene (GNP), 0.5%, 5%, 10%, were obtained using injection mold...

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Detalles Bibliográficos
Autores principales: Hajduga, Maciej B., Bobinski, Rafał, Dutka, Mieczysław, Bujok, Jan, Cwiertnia, Michał, Pajak, Celina, Kurowska, Anna, Rajzer, Izabella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9500631/
https://www.ncbi.nlm.nih.gov/pubmed/36142811
http://dx.doi.org/10.3390/ijms231810899
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author Hajduga, Maciej B.
Bobinski, Rafał
Dutka, Mieczysław
Bujok, Jan
Cwiertnia, Michał
Pajak, Celina
Kurowska, Anna
Rajzer, Izabella
author_facet Hajduga, Maciej B.
Bobinski, Rafał
Dutka, Mieczysław
Bujok, Jan
Cwiertnia, Michał
Pajak, Celina
Kurowska, Anna
Rajzer, Izabella
author_sort Hajduga, Maciej B.
collection PubMed
description This work contains an analysis of the impact of modifying a bioresorbable polymer—polycaprolactone (PCL)—with various additives on its antibacterial properties. To this end, samples of PCL filament containing various content levels of graphene (GNP), 0.5%, 5%, 10%, were obtained using injection molding. Polymer samples without additives were used for comparison. The next step was to assess the antimicrobial impact of the preparations under study against the following microorganisms: Staphylococcus aureus ATCC 25293, Escherichia coli ATCC 25922, Candida albicans ATCC 10231. Effective bactericidal activity of PCL with small amount of GNP, especially against C. albicans and S. aureus was confirmed. A decrease in this property or even multiplication of microorganisms was observed in direct proportion to the graphene content in the samples.
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spelling pubmed-95006312022-09-24 The Influence of Graphene Content on the Antibacterial Properties of Polycaprolactone Hajduga, Maciej B. Bobinski, Rafał Dutka, Mieczysław Bujok, Jan Cwiertnia, Michał Pajak, Celina Kurowska, Anna Rajzer, Izabella Int J Mol Sci Article This work contains an analysis of the impact of modifying a bioresorbable polymer—polycaprolactone (PCL)—with various additives on its antibacterial properties. To this end, samples of PCL filament containing various content levels of graphene (GNP), 0.5%, 5%, 10%, were obtained using injection molding. Polymer samples without additives were used for comparison. The next step was to assess the antimicrobial impact of the preparations under study against the following microorganisms: Staphylococcus aureus ATCC 25293, Escherichia coli ATCC 25922, Candida albicans ATCC 10231. Effective bactericidal activity of PCL with small amount of GNP, especially against C. albicans and S. aureus was confirmed. A decrease in this property or even multiplication of microorganisms was observed in direct proportion to the graphene content in the samples. MDPI 2022-09-17 /pmc/articles/PMC9500631/ /pubmed/36142811 http://dx.doi.org/10.3390/ijms231810899 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Hajduga, Maciej B.
Bobinski, Rafał
Dutka, Mieczysław
Bujok, Jan
Cwiertnia, Michał
Pajak, Celina
Kurowska, Anna
Rajzer, Izabella
The Influence of Graphene Content on the Antibacterial Properties of Polycaprolactone
title The Influence of Graphene Content on the Antibacterial Properties of Polycaprolactone
title_full The Influence of Graphene Content on the Antibacterial Properties of Polycaprolactone
title_fullStr The Influence of Graphene Content on the Antibacterial Properties of Polycaprolactone
title_full_unstemmed The Influence of Graphene Content on the Antibacterial Properties of Polycaprolactone
title_short The Influence of Graphene Content on the Antibacterial Properties of Polycaprolactone
title_sort influence of graphene content on the antibacterial properties of polycaprolactone
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9500631/
https://www.ncbi.nlm.nih.gov/pubmed/36142811
http://dx.doi.org/10.3390/ijms231810899
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