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Synthetic gRNA/Cas9 Ribonucleoprotein Inhibits HIV Reactivation and Replication
The current antiretroviral therapy (ART) for human immunodeficiency virus (HIV) can halt viral replication but cannot eradicate HIV infection because proviral DNA integrated into the host genome remains genetically silent in reservoir cells and is replication-competent upon interruption or cessation...
Autores principales: | Khanal, Sushant, Cao, Dechao, Zhang, Jinyu, Zhang, Yi, Schank, Madison, Dang, Xindi, Nguyen, Lam Ngoc Thao, Wu, Xiao Y., Jiang, Yong, Ning, Shunbin, Zhao, Juan, Wang, Ling, Gazzar, Mohamed El, Moorman, Jonathan P., Yao, Zhi Q. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9500661/ https://www.ncbi.nlm.nih.gov/pubmed/36146709 http://dx.doi.org/10.3390/v14091902 |
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