Cargando…

Synthesis, Neuroprotective Effect and Physicochemical Studies of Novel Peptide and Nootropic Analogues of Alzheimer Disease Drug

Glutamate is an excitatory neurotransmitter in the nervous system. Excessive glutamate transmission can lead to increased calcium ion expression, related to increased neurotoxicity. Memantine is used for treating patients with Alzheimer’s disease (AD) due to its protective action on the neurons agai...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chayrov, Radoslav, Volkova, Tatyana, Perlovich, German, Zeng, Li, Li, Zhuorong, Štícha, Martin, Liu, Rui, Stankova, Ivanka
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9500833/ https://www.ncbi.nlm.nih.gov/pubmed/36145329 http://dx.doi.org/10.3390/ph15091108

Ejemplares similares

Synthetic Analogues of Aminoadamantane as Influenza Viral Inhibitors—In Vitro, In Silico and QSAR Studies
por: Chayrov, Radoslav, et al.
Publicado: (2020)

Physicochemical Profile of Antiandrogen Drug Bicalutamide: Solubility, Distribution, Permeability
por: Volkova, Tatyana V., et al.
Publicado: (2022)

Nootropic and Neuroprotective Effects of Dichrocephala integrifolia on Scopolamine Mouse Model of Alzheimer’s Disease
por: Kouémou, Nadège E., et al.
Publicado: (2017)

Revisiting the Solubility–Permeability Relationship with Hydrophobic Drug Umifenovir in Pluronic Solutions: Impact of pH and Co-Solvent
por: Volkova, Tatyana, et al.
Publicado: (2023)

Modulation of Distribution and Diffusion through the Lipophilic Membrane with Cyclodextrins Exemplified by a Model Pyridinecarboxamide Derivative
por: Volkova, Tatyana, et al.
Publicado: (2023)

Permeability of New Antifungal Fluconazole Derivatives through a Lipophilic Membrane: Experiment and Modeling
por: Volkova, Tatyana V., et al.
Publicado: (2023)

Cyclodextrin’s Effect on Permeability and Partition of Nortriptyline Hydrochloride
por: Volkova, Tatyana, et al.
Publicado: (2023)

Evaluation of nootropic and neuroprotective effects of low dose aspirin in rats
por: Ghosh, Arijit, et al.
Publicado: (2011)

Chemical Stability of New Acyclovir Analogues with Peptidomimetics
por: Hristov, Georgi, et al.
Publicado: (2011)

New Antifungal Compound: Impact of Cosolvency, Micellization and Complexation on Solubility and Permeability Processes
por: Volkova, Tatyana V., et al.
Publicado: (2021)

Another Move towards Bicalutamide Dissolution and Permeability Improvement with Acetylated β-Cyclodextrin Solid Dispersion
por: Volkova, Tatyana V., et al.
Publicado: (2022)

Establishing Natural Nootropics: Recent Molecular Enhancement Influenced by Natural Nootropic
por: Suliman, Noor Azuin, et al.
Publicado: (2016)

The Nootropic Drug A-Glyceryl-Phosphoryl-Ethanolamine Exerts Neuroprotective Effects in Human Hippocampal Cells
por: Daniele, Simona, et al.
Publicado: (2020)

Chiral Recognition R- and RS- of New Antifungal: Complexation/Solubilization/Dissolution Thermodynamics and Permeability Assay
por: Volkova, Tatyana V., et al.
Publicado: (2022)

The effectiveness of Bacopamonnieri (Linn.) Wettst. as a nootropic, neuroprotective, or antidepressant supplement: analysis of the available clinical data
por: Brimson, James M., et al.
Publicado: (2021)

Nootropics with potential to (re)build neuroarchitecture
por: Koshibu, Kyoko
Publicado: (2016)

The Safety and Efficacy of Botanicals with Nootropic Effects
por: Roe, Amy L., et al.
Publicado: (2021)

Neuroprotective and nootropic activity of Clitorea ternatea Linn.(Fabaceae) leaves on diabetes induced cognitive decline in experimental animals
por: Talpate, Karuna A., et al.
Publicado: (2014)

Nootropic herbs (Medhya Rasayana) in Ayurveda: An update
por: Kulkarni, Reena, et al.
Publicado: (2012)

MicroRNA-200a-3p Mediates Neuroprotection in Alzheimer-Related Deficits and Attenuates Amyloid-Beta Overproduction and Tau Hyperphosphorylation via Coregulating BACE1 and PRKACB
por: Wang, Linlin, et al.
Publicado: (2019)

Central depressant and nootropic effects of daytime melatonin in mice
por: Onaolapo, Olakunle J, et al.
Publicado: (2014)

Enhancement of nootropic effect of duloxetine and bupropion by caffeine in mice
por: Kale, Pravin Popatrao, et al.
Publicado: (2015)

Anxiolytic and nootropic activity of Vetiveria zizanioides roots in mice
por: Nirwane, Abhijit M., et al.
Publicado: (2015)

Biomolecular Evaluation of Lavandula stoechas L. for Nootropic Activity
por: Mushtaq, Aamir, et al.
Publicado: (2021)

Nootropic Herbs, Shrubs, and Trees as Potential Cognitive Enhancers
por: Malík, Matěj, et al.
Publicado: (2023)

Formation Thermodynamics of Carbamazepine with Benzamide, Para-Hydroxybenzamide and Isonicotinamide Cocrystals: Experimental and Theoretical Study
por: Manin, Alex N., et al.
Publicado: (2022)

Screening and personalizing nootropic drugs and cognitive modulator regimens in silico
por: Jellen, Leslie C., et al.
Publicado: (2015)

Nootropic Effects of C. melo and C. lanatus seed extracts
por: Wahid, Shahana, et al.
Publicado: (2020)

Microarray Profile of Long Noncoding RNA and Messenger RNA Expression in a Model of Alzheimer’s Disease
por: Wang, Linlin, et al.
Publicado: (2020)

Nootropic activity of acetaminophen against colchicine induced cognitive impairment in rats
por: Pitchaimani, Vigneshwaran, et al.
Publicado: (2012)

Cannabis-induced impairment of learning and memory: effect of different nootropic drugs
por: Abdel-Salam, Omar M.E., et al.
Publicado: (2013)

Nootropic (medhya) effect of Bhāvita Śaṇkhapuṣpī tablets: A clinical appraisal
por: Amin, Hetal, et al.
Publicado: (2014)

Differential effect of Ayurvedic nootropics on C. elegans models of Parkinson’s disease
por: Anjaneyulu, Jalagam, et al.
Publicado: (2020)

Liver proteome alterations in psychologically distressed rats and a nootropic drug
por: González-Fernández, Raquel, et al.
Publicado: (2021)

Nootropics as Cognitive Enhancers: Types, Dosage and Side Effects of Smart Drugs
por: Malík, Matěj, et al.
Publicado: (2022)

New Solid Forms of Nitrofurantoin and 4-Aminopyridine Salt: Influence of Salt Hydration Level on Crystal Packing and Physicochemical Properties
por: Boycov, Denis E., et al.
Publicado: (2022)

Chromatographic Behaviour Predicts the Ability of Potential Nootropics to Permeate the Blood-Brain Barrier
por: Farsa, Oldřich
Publicado: (2013)

The Combination of Antidepressant Duloxetine with Piracetam in Mice does not Produce Enhancement of Nootropic Activity
por: Kale, Pravin Popatrao, et al.
Publicado: (2014)

Effectiveness of nootropic drugs with cholinergic activity in treatment of cognitive deficit: a review
por: Colucci, Luisa, et al.
Publicado: (2012)

Identifying nootropic drug targets via large-scale cognitive GWAS and transcriptomics
por: Lam, Max, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_molgkvnrsm7h58h7ef5o8d3ppr